The chances of developing histoplasmosis symptoms increase with the number of spores you inhale. Professions with a higher likelihood of spore exposure include:

  • Farmers
  • Pest control workers
  • Poultry keepers
  • Construction workers
  • Roofers
  • Landscapers and gardeners

Most at risk of severe infection

Very young children and older adults have weaker immune systems, so they're more likely to develop disseminated histoplasmosis — the most serious form of the disease. Other factors that can weaken your immune system include:

  • HIV or AIDS
  • Cancer chemotherapy
  • Corticosteroid drugs, such as prednisone
  • TNF inhibitors, often used to control rheumatoid arthritis
  • Medications that prevent rejection of organ transplants
Feb. 08, 2012

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