As a major heart failure research center, Mayo Clinic focuses on the detection and diagnosis of heart failure in its earliest stages. Mayo Clinic researchers study investigational and new treatments for people who have congestive heart failure. Mayo Clinic is part of the National Institutes of Health Heart Failure Clinical Research Network.
You may have the opportunity to participate in clinical trials of experimental therapies not available at all medical centers. Learn more about cardiovascular research at the research website.
Mayo Clinic publications
See a list of publications by Mayo Clinic doctors on congestive heart failure on PubMed, a service of the National Library of Medicine.
Investigational treatment studies
Mayo Clinic investigators are studying several potential therapies for congestive heart failure, including:
Aug. 16, 2013
- New surgical approaches. Mayo Clinicsurgeons are studying new left ventricular assist devices, surgical and nonsurgical valve repair and replacement, and heart muscle surgeries.
- Artificial heart. An all-mechanical artificial heart exists for special situations, usually for patients waiting for a heart transplant. This device replaces the function of both sides of your heart.
- New drugs. Mayo Clinic researchers are testing new drugs that may help people who have heart failure. Researchers developed these drugs by modifying the heart's defense system (natriuretic peptide system) to create drugs that may enhance heart and kidney function.
- What is heart failure? National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/hf/. Accessed May 3, 2013.
- Papadakis MA, et al. Current Medical Diagnosis & Treatment 2013. 52nd ed. New York, N.Y.: The McGraw-Hill Companies; 2013. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=1. Accessed May 3, 2013.
- Lindenfield J, et al. 2010 HFSA Comprehensive practice guideline. Journal of Cardiac Failure. 2010;16:475.
- Heart failure. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merckmanuals.com/professional/cardiovascular_disorders/heart_failure/heart_failure_hf.html#v935853. Accessed May 6, 2013.
- Weintraub NL, et al. Acute heart failure syndromes: Emergency department presentation, treatment and disposition - Current approaches and future aims. Circulation. 2010;122:1975.
- Ramachandran SV, et al. Epidemiology and causes of heart failure. http://www.uptodate.com/home. Accessed May 5, 2013.
- Schocken DD, et al. Prevention of heart failure: A scientific statement from the American Heart Association. Circulation. 2008;117:2544.
- Yancy CW, et al. 2013 ACCF/AHA guideline for the management of heart failure. Journal of the American College of Cardiology. [In press]. Accessed June 9, 2013. [date].
- Horwitz L, et al. Heart failure self-management. http://www.uptodate.com/home. Accessed May 5, 2013.
- Riegel B, et al. State of the science: Promoting self-care in persons with heart failure — A scientific statement from the American Heart Association. Circulation. 2009;120:1141.
- U.S. News best hospitals 2012-2013. U.S. News & World Report. http://health.usnews.com/best-hospitals/rankings. Accessed Feb. 1, 2013.
- Grogan M (expert opinion). Mayo Clinic, Rochester, Minn.
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