H. pylori infections are usually treated with two varieties of antibiotics at once, to help prevent the bacteria from developing a resistance to one particular antibiotic. Your doctor also will prescribe an acid-suppressing drug, to help your stomach lining heal.
Drugs that can suppress acid include:
- Proton pump inhibitors (PPIs). These drugs stop acid from being produced in the stomach. Some examples of PPIs are omeprazole (Prilosec, others), esomeprazole (Nexium, others), lansoprazole (Prevacid, others) and pantoprazole (Protonix, others).
- Histamine (H-2) blockers. These medications block a substance called histamine, which triggers acid production. Examples include cimetidine (Tagamet) and ranitidine (Zantac).
- Bismuth subsalicylate. More commonly known as Pepto-Bismol, this drug works by coating the ulcer and protecting from stomach acid.
Your doctor may recommend that you undergo testing for H. pylori at least four weeks after your treatment. If the tests show the treatment was unsuccessful, you may undergo another round of treatment with a different combination of antibiotic medications.
June 05, 2014
- H. pylori and peptic ulcers. National Institute of Diabetes and Digestive and Kidney Diseases. http://digestive.niddk.nih.gov/ddiseases/pubs/hpylori/. Accessed Dec. 30, 2013.
- Papadakis MA, ed., et al. Current Medical Diagnosis & Treatment 2014. 53rd ed. New York, N.Y.: The McGraw-Hill Companies; 2014. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=1. Accessed Dec. 31, 2013.
- Helicobacter pylori infection. The Merck Manuals: The Merck Manual for Health Care Professionals. http://www.merckmanuals.com/professional/gastrointestinal_disorders/gastritis_and_peptic_ulcer_disease/helicobacter_pylorihelicobacter_pylori_infection.html. Accessed Jan. 3, 2014.
- Helicobacter pylori and cancer. National Cancer Institute. http://www.cancer.gov/cancertopics/factsheet/Risk/h-pylori-cancer. Accessed Jan. 3, 2014.
- Chey W, et al. American College of Gastroenterology guideline on the management of Helicobacter pylori infection. Bethesda, Md.: American College of Gastroenterology. http://gi.org/guideline/management-of-helicobacter-pylori-infection/. Accessed Dec. 30, 2013.
- Crowe SE. Bacteriology and epidemiology of Helicobacter pylori infection. http://www.uptodate.com/home. Accessed Dec. 30, 2013.
- Crowe SE. Indications and diagnostic tests for Helicobacter pylori infection. http://www.uptodate.com/home. Accessed Dec. 30, 2013.
You Are ... The Campaign for Mayo Clinic
Mayo Clinic is a not-for-profit organization. Make a difference today.