As with many mental health conditions, what causes generalized anxiety disorder isn't fully understood. It may involve naturally occurring brain chemicals (neurotransmitters), such as serotonin, dopamine and norepinephrine. It's likely that the condition has several causes that may include genetics, your life experiences and stress.

Some physical health conditions are associated with anxiety. Examples include:

  • Gastroesophageal reflux disease (GERD)
  • Heart disease
  • Hypothyroidism or hyperthyroidism
  • Menopause
Sep. 08, 2011

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