For more than 30 years, the Mayo Clinic Department of Ophthalmology has conducted research related to Fuchs' dystrophy and cornea transplantation. A Mayo Clinic eye doctor and researcher helped develop an advanced clinical specular microscopy technique, which allows corneal endothelial cells in the normal, diseased and transplanted cornea to be imaged and evaluated. It's a crucial resource today for understanding cornea and cornea transplant function.

Mayo Clinic researchers are assessing outcomes of new cornea transplant techniques for people with corneal swelling from diseases such as Fuchs' dystrophy. Prospective studies assessing the changes that are smaller than those which can be seen with the ordinary light microscope (ultrastructural corneal changes) in Fuchs' dystrophy also are in progress.

In addition, researchers at Mayo Clinic recently identified the first genetic link (association) for the common form of Fuchs' dystrophy. Researchers are conducting lab studies to determine the underlying causes of Fuchs' dystrophy and the factors involved in disease progression.Read more about cornea research at Mayo Clinic.

Publications

See a list of publications by Mayo Clinic doctors on Fuchs' dystrophy on PubMed, a service of the National Library of Medicine.

Jul. 16, 2011