Anyone can develop an enlarged spleen at any age, but certain groups are at higher risk, including:
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- Children and young adults with infections, such as mononucleosis
- People who have Gaucher's disease, Niemann-Pick disease, and several other inherited metabolic disorders affecting the liver and spleen
- People who live in or travel to areas where malaria is endemic
- Landaw SA, et al. Approach to the adult patient with splenomegaly and other splenic disorders. http://www.uptodate.com/home. Accessed June 6, 2013.
- Splenomegaly. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merckmanuals.com/professional/hematology_and_oncology/spleen_disorders/splenomegaly.html. Accessed June 6, 2013.
- Longo DL, et al. Harrison's Online. 18th ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=4. Accessed June 6, 2013.
- Pozo AL, et al. Splenomegaly: Investigation, diagnosis and management. Blood Reviews. 2009;23:105.
- Recommended Adult Immunization Schedule: United States — 2013. Centers for Disease Control and Prevention. http://www.cdc.gov/vaccines/schedules/hcp/adult.html. Accessed June 6, 2013.