A larger-than-normal liver may be a sign of a wide range of diseases. Although diseases of the liver itself often cause an enlarged liver, there are many other possible causes, including:

  • Bacteria, viruses and parasites
  • Certain heart conditions
  • Several genetic diseases
  • Some types of leukemia and lymphoma

The liver, a wedge-shaped organ on the right side of your upper abdomen, is the largest internal organ. An adult liver normally weighs between 2.6 and 3.3 pounds (1.2 to 1.5 kg) and measures an average of 5.9 inches (15 cm) in width.

It's very unusual to have an enlarged liver without other signs and symptoms that point to an underlying disease.

Nov. 27, 2015