Treatment for mild cases, which may be mistaken as the flu, mainly consists of:
- Bed rest
- Plenty of fluids
- Anti-inflammatory drugs— such as acetaminophen (Tylenol, others), ibuprofen (Advil, Motrin IB, others) and naproxen sodium (Aleve, others) — to relieve headaches and fever.
Cases of encephalitis due to certain viruses usually require intravenous antiviral treatments. Antiviral drugs commonly used to treat encephalitis include:
- Acyclovir (Zovirax)
- Ganciclovir (Cytovene)
- Foscarnet (Foscavir)
Some viruses, such as insect-borne viruses, don't respond to these treatments. However, because the specific virus may not be identified immediately or at all, treatment with acyclovir is often begun immediately. This drug can be effective against the herpes simplex virus, which can result in significant complications, such as encephalitis, or death when not treated promptly.
Side effects of antiviral drugs may include nausea, vomiting, diarrhea, and muscle or joint soreness or pain. Rare serious problems may include abnormalities in kidney or liver function or suppression of bone marrow activity. Appropriate tests are used to monitor for serious adverse effects.
Additional supportive care also is needed in the hospital for people with severe encephalitis. The care may include:
- Breathing assistance, as well as careful monitoring of breathing and heart function
- Intravenous fluids to ensure proper hydration and appropriate levels of essential minerals
- Anti-inflammatory drugs, such as corticosteroids, to help reduce swelling and pressure within the skull
- Anticonvulsant medications, such as phenytoin (Dilantin), to stop or prevent seizures.
After the initial illness, it may be necessary to receive additional therapy depending on the type and severity of complications. This therapy may include:
May. 15, 2014
- Physical therapy to improve strength, flexibility, balance, motor coordination and mobility
- Occupational therapy to develop everyday skills and to use adaptive products that help with everyday activities
- Speech therapy to relearn muscle control and coordination to produce speech
- Psychotherapy to learn coping strategies and new behavioral skills to improve mood disorders or address personality changes — with medication management if necessary
- Longo DL, et al. Harrison's Online. 18th ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=4. Accessed Feb. 15, 2014.
- Encephalitis and meningitis fact sheet. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/encephalitis_meningitis/detail_encephalitis_meningitis.htm. Accessed Feb. 17, 2014.
- Encephalitis. The Merck Manuals: The Merck Manual for Health Care Professionals. http://www.merckmanuals.com/professional/neurologic_disorders/brain_infections/encephalitis.html. Accessed Feb. 17, 2014.
- Hardarson HS. Acute viral encephalitis in children and adolescents: Clinical manifestations and diagnosis. http://www.uptodate.com/home. Accessed Feb. 15. 2014.
- Johnson RP, et al. Viral encephalitis in adults. http://www.uptodate.com/home. Accessed Feb. 15, 2014.
- Hardarson HS. Acute viral encephalitis in children and adolescents: Pathogenesis and etiology. http://www.uptodate.com/home. Accessed Feb. 15, 2014.
- Hardarson HS. Acute viral encephalitis in children and adolescents: Treatment and prevention. http://www.uptodate.com/home. Accessed Feb. 15, 2014.
- FAQ: Insect repellant use and safety. Centers for Disease Control and Prevention. http://www.cdc.gov/westnile/faq/repellent.html. Accessed Feb. 17, 2014.
- Insect repellent use and safety in children. U.S. Food and Drug Administration. http://www.fda.gov/Drugs/EmergencyPreparedness/ucm085277.htm. Accessed Feb. 17, 2014.
- Prevention & control. Centers for Disease Control and Prevention. http://www.cdc.gov/westnile/prevention/index.html. Accessed Feb. 17, 2014.
You Are ... The Campaign for Mayo Clinic
Mayo Clinic is a not-for-profit organization. Make a difference today.