In corticobasal degeneration, areas of your brain (including the cerebral cortex and basal ganglia) shrink and your nerve cells degenerate and die over time. This degeneration results in growing difficulty in movement on one or both sides of your body.
The condition may cause you to have poor coordination, stiffness, tremor, thinking (cognitive) difficulties, speech difficulty or other problems.
March 12, 2014
- NINDS corticobasal degeneration information page. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/corticobasal_degeneration/corticobasal_degeneration.htm. Accessed Sept. 9, 2013.
- Corticobasal degeneration. http://www.uptodate.com/home. Accessed Sept. 3, 2013.
- Boeve BF. Parkinson-related dementias. Neurologic Clinics. 2007;25:761.
- Kouri N, et al. Corticobasal degeneration: A pathologically distinct 4R tauopathy. Nature Reviews. Neurology. 2011;7:263.
- Riggin EA. Decision Support System. Mayo Clinic, Rochester, Minn. Aug. 29, 2013.
- Shadlen MF, et al. Evaluation of cognitive impairment and dementia. http://www.uptodate.com/home. Accessed Sept. 9, 2013.
- Neurological diagnostic tests and procedures. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/misc/diagnostic_tests.htm. Accessed Sept. 9, 2013.
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