C. difficile infection care at Mayo Clinic

Mayo Clinic specializes in treating people with difficult cases of C. difficile who haven't responded to standard medical treatments or who have developed complications such as an inflamed colon. The Division of Gastroenterology and Hepatology at Mayo Clinic in Rochester, Minnesota, opened a C. difficile clinic that specializes in treating patients with C. difficile infection.

Your Mayo Clinic care team

Mayo Clinic uses a multidisciplinary team approach to evaluation and management of C. difficile infection with a team consisting of physicians, nurses, study coordinators and laboratory personnel. Doctors who specialize in digestive and infectious diseases work closely with laboratory medicine specialists and scientists specializing in the gut microbiome and individualized medicine to diagnose and treat your condition.

Advanced diagnosis and treatment

Mayo Clinic uses the polymerase chain reaction (PCR) test, the most accurate diagnostic test available to confirm C. difficile infection. The high sensitivity of PCR, together with its rapid turnaround time, allows prompt treatment for people with C. difficile infection, likely reducing opportunity for spreading infection and improving outcomes.

For recurrent or stubborn C. difficile infections, the fecal microbiota transplant (FMT) has been performed at Mayo Clinic with a success rate higher than 90 percent. FMT therapy involves infusing healthy donor stools in people with C. difficile infections. Mayo Clinic performs extensive testing of donors and recipients before performing the procedure and offers the choice of related (family) or standard donors. Because donor testing typically isn't covered by insurance, Mayo Clinic has a standard donor pool to help reduce the cost to potential recipients. Mayo Clinic also participates in clinical trials that are studying enema and capsule formulations for FMT.

Fecal transplant treatment of C. difficile at Mayo Clinic

Watch Sahil Khanna, M.B.B.S., a Mayo Clinic gastroenterologist, discuss fecal transplant treatment of C. difficile at Mayo Clinic

Mayo Clinic study reporting increased incidence of C. difficile infection

June 18, 2016
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