Risk factors for adenomyosis include:

  • Prior uterine surgery, such as a C-section or fibroid removal
  • Childbirth
  • Middle age

Most cases of adenomyosis — which depends on estrogen — are found in women in their 40s and 50s. Adenomyosis in middle-aged women could relate to longer exposure to estrogen compared with that of younger women. Until recently, adenomyosis was most often diagnosed only when a woman had a hysterectomy. Current research suggests that the condition may also be common, but often undetected, in younger women.

April 02, 2015