Pediatric Metabolic Bone Disorders Clinic

Mayo's Pediatric Metabolic Bone Disorders Clinic provides comprehensive and coordinated care for children and teenagers with all types of skeletal diseases, including complex and rare conditions. Examples include:

  • Osteogenesis imperfecta, sometimes called brittle bone disease
  • Vitamin D disorders
  • Hypophosphatemic rickets, a type of rickets associated with low phosphate levels
  • Hypophosphatasia (HPP), a disorder causing abnormal development of bones and teeth
  • Skeletal dysplasias, a group of disorders that involve abnormal bone formation and growth
  • Albright hereditary osteodystrophy (pseudohypoparathyroidism), a disorder involving the inability to respond to parathyroid hormone, affecting bone growth and height
  • Fibrous dysplasia/McCune Albright syndrome, a disorder that affects bones, skin pigment and the endocrine system
  • Juvenile Paget disease, a disorder that causes bones to be abnormally large, deformed and weak
  • High bone mass disorders
  • Extraskeletal calcification disorders

Team approach, tailored to your child's needs

A multispecialty approach to diagnosis and treatment provided by a team of experts is essential for the best outcomes. Depending on your child's needs, our comprehensive care team includes highly skilled experts from these areas at Mayo Clinic:

If needed, additional experts may be involved in developing a unified and personalized plan of care for your child.


Make an appointment at Mayo Clinic Children's Center and learn about patient services.

Genetic Bone Diseases in Children