Autosomal recessive inheritance pattern

In an autosomal recessive disorder, two changed genes are inherited, one from each parent. The parents' health is rarely affected because they have only one changed gene. Two carriers have a 25% chance of having an unaffected child with two unaffected genes. They have a 50% chance of having an unaffected child who also is a carrier. They have a 25% chance of having an affected child with two changed genes.

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