Biographical summary
Dr. Keegan trained in Neurology at the University of Saskatchewan in Saskatoon, Canada. He then completed two years subspecialty fellowship in Neuroimmunology and Multiple Sclerosis at Mayo Clinic in Rochester Minnesota. He joined the faculty of the Mayo Clinic in 2001 where he is a Consultant, Professor of Neurology and Head of the Division of Multiple Sclerosis and Autoimmune Neurology.
He is a clinician and performs clinically-based and translational research including clinical presentations of MS and its mimickers, paraneoplastic myelopathies, progressive MS and the use of plasma exchange for severe multiple sclerosis attacks. His research is published in high quality journals including Lancet, Brain, Neurology, Annals of Neurology and JAMA Neurology.
Relevant publications include defining progressive solitary sclerosis, and "paucisclerotic" MS showing that severe MS progression may occur from a single definable MS plaque, defining clinical factors that are associated with improved patient response to plasma exchange including the first study to clearly show a difference in patient response to MS therapy based on pathological subtype. He defined a unique inflammatory CNS disease syndrome that he named Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids or "CLIPPERS" and leads an international consortium aimed at elucidating its etiology and optimal treatments.
He is the principal investigator for Mayo Clinic on a number of multi-center therapeutic clinical trials in MS. He was the founding section editor of the Clinical Pathological Cases for the journal Neurology, a chief Editor of eMedicine and he is on the Editorial board of MS and Related Disorders. His book Common Pitfalls in Multiple Sclerosis and CNS Demyelinating Diseases was recently published by Cambridge University Press.
Conditions treated
Interests
- Demyelinating diseases
- Multiple sclerosis
Mayo Clinic locations
Education
- 2001
ResidentNeuro-immunology, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
- 2001
Fellow - NeuroimmunologyMayo Clinic in Rochester
- 1999
Resident - Chief Neurology ResidentDivision of Neurology, University of Saskatchewan
- 1998
Resident - NeurologyDivision of Neurology, University of Saskatchewan
- 1994
MDMedical School, University of Saskatchewan
- 1990
BA - PsychologyCollege of Arts and Sciences, University of Saskatchewan
Activities and honors
Certifications
- 2001
NeurologyAmerican Board of Psychiatry and Neurology
- 1999
NeurologyRoyal College of Physicians & Surgeons of Canada
Awards and honors
- 2011
Top Educator Residency ProgramDepartment of Internal Medicine
- 2009
Top EducatorDepartment of Internal Medicine
- 2008
Top EducatorInternal Medicine Residency Program, Department of Internal Medicine
- 2003
Young Investigator Congress GrantEuropean Committtee for Treatment and Research in Multiple Sclerosis (ECTRIMS)
- 2001
Excellence in Teaching RecognitionMayo Medical School, Mayo Clinic College of Medicine and Science, Department of Education Administration
- 1994
Graduated with DistinctionCollege of Medicine, University of Saskatchewan
- 1992
Fisons Award in Immunology and AllergyAwarding Organization
- 1990
Magna Cum LaudeCollege of Arts and Sciences, University of Saskatchewan
Professional memberships
- 2018 - present
FellowAmerican Academy of Neurology
- 2016 - present
Breakthroughs in Neurology Conference Work GroupAmerican Academy of Neurology
- 2015 - 2017
MemberPractice Committee, American Academy of Neurology
- 2015 - present
Advisory Council MemberAmericas Committee for Treatment & Research in Multiple Sclerosis (ACTRIMS)
- 2012 - present
Associate Chair for Clinical PracticeNeurology Practice Committee, Department of Neurology
- 2012 - present
MemberAmerican Neurological Association
- 2012 - present
FellowAmerican Neurological Association
- 2011
Invited Expert ReviewerendMS Research and Training Network Grant, Multiple Sclerosis Society of Canada
- 2011 - present
MemberNeurology Executive Committee, Department of Neurology
- 2010 - present
MemberSection of Multiple Sclerosis, American Academy of Neurology
- 2009 - present
Division Chair MS and Autoimmune NeurologyDepartment of Neurology
- 2009 - present
MemberDepartment of Neurology
- 2009 - 2012
Assistant Clinical Practice ChairNeurology Practice Committee, Department of Neurology
- 2009 - present
MemberNeurology Practice Committee, Department of Neurology
- 2009 - present
MemberQuality Subcommittee, Department of Neurology
- 2009 - present
MemberDoctors Mayo Society, Mayo Clinic Alumni Association, Mayo Clinic College of Medicine and Science
- 2008 - present
MemberAsk Mayo Expert Advisory Group, Education Technology Center, Department of Education Administration
- 2006 - 2011
DirectorNeurology Conferences, Department of Neurology
- 2005 - 2010
MemberEducation Committee, Department of Neurology
- 2005 - 2010
MemberResident Education Committee, Department of Neurology
- 2003 - 2008
MemberSpinal Cord Injury Interdisciplinary Committee, Mayo Clinic Rochester Committees
- 1999 - present
MemberAmerican Medical Association
- 1999 - present
MemberMinnesota Medical Association
- 1996 - present
MemberAmerican Academy of Neurology
-
MemberContributor, Mayo Clinic Family Health Book, Office of Intellectual Property (formerly Mayo Medical Ventures)
Publications
Research activities