Proper Use

Drug information provided by: Merative, Micromedex®

Do not use this medicine for a headache that is different from your usual migraines. Talk to your doctor about what to do for regular headaches.

To relieve your migraine as soon as possible, use this medicine as soon as the headache pain begins.

Lying down in a quiet, dark room for a while after you use this medicine may help relieve your migraine.

Zecuity® is an iontophoretic transdermal system (TDS) or a device-assisted skin patch that uses a mild electrical current to deliver sumatriptan through your skin.

This medicine comes with a patient information leaflet. Read and follow the instructions carefully. Ask your doctor or pharmacist if you have any questions.

To use the Zecuity® patch:

  • Use this medicine exactly as directed by your doctor. It will work only if it has been applied correctly.
  • This medicine should only be used on skin that is not irritated or injured. Do not put the patch in your mouth, chew it, or swallow it.
  • Sumatriptan skin patches are packaged in sealed pouches. Do not use this medicine if the pouch seal is broken or if the patch is cut, damaged, or changed in any way.
  • Wash your hands with soap and water before and after applying a patch.
  • To apply the patch, pull the two foil tabs and rub each foil packet tracing the green arrow 3 times around. Unfold and lift open the package. Slowly peel the liner and check if the medication pads are securely attached.
  • Apply the patch to a dry, intact, flat skin area on your upper arm or thigh. Choose a place where the skin is not very oily and is free of scars, tattoos, cuts, burns, scratches, or irritation. The application site should be free from redness or irritation for at least 3 days before applying a new patch.
  • The patch will stay in place better if it is applied to an area with little or no hair. If you need to apply the patch to a hairy area, you may first clip the hair with scissors, but do not shave it off.
  • After applying the patch, push the activation button and a red light emitting diode (LED) will turn on. The patch must be applied and activated within 15 minutes after removing the foil tabs.
  • If the patch becomes loose, tape the edges with a medical tape.
  • If the activation light turns off before 4 hours, the patch can be removed. Remove it slowly to avoid skin irritation. Clean the area gently with a mild soap and water to remove any medicine left on the skin.
  • Keep the patch dry. Do not bathe, shower, or swim while using this medicine.
  • Remove Zecuity® patch and call your doctor right away if you feel moderate to severe pain at the patch site. This is to avoid serious burns and possible scars at the patch site.
  • If your headache comes back or gets worse after a while, you may apply a second patch to your other arm or thigh and wait for at least 2 hours after activation of the first applied patch.


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For transdermal dosage form (skin patch):
    • For migraine headaches:
      • Adults—One patch applied to the skin and left in place for 4 hours. Do not use more than two Zecuity® patches in a 24-hour period.
      • Children—Use and dose must be determined by your doctor.

Missed Dose

If you forget to wear or change a patch, put one on as soon as you can. If it is almost time to put on your next patch, wait until then to apply a new patch and skip the one you missed. Do not apply extra patches to make up for a missed dose.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

This medicine contains lithium-manganese dioxide batteries. Talk to your doctor or pharmacist about how to follow state and local regulations when throwing away this medicine.

To dispose of this medicine, fold the patch in half with the sticky side inside. Then throw it properly in a trash can.