Proper Use

Drug information provided by: Merative, Micromedex®

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

This medicine should come with a patient information leaflet. Read and follow these instructions carefully. Ask your doctor if you have any questions.

Swallow the delayed-release tablet whole. Do not crush, break, or chew it. You may take this medicine with or without food.

If you are using the oral liquid:

  • Shake the oral liquid well before measuring the dose. Use the dosing spoon in the package to measure the dose. The average household teaspoon may not hold the right amount of liquid. Rinse the measuring spoon with water after using and before storage.
  • Take this medicine during or right after (within 20 minutes) a full meal or liquid nutritional supplement. This medicine may also be taken with an acidic beverage (eg, ginger ale).

If you are using the delayed-release oral liquid:

  • Do not open the pack until ready to prepare the medicine.
  • Remove the cap from the mixing liquid and push the bottle adapter into the neck of the bottle. Remove 9 milliliters (mL) of mixing liquid using the provided blue syringe and put back the cap on the bottle. Use only the provided mixing liquid and syringes.
  • Mix the 9 mL liquid and the entire contents of 1 packet in the provided mixing cup. Shake the cup for 45 seconds and make sure the powder is mixed. The mixture should look cloudy and free from clumps.
  • Take the liquid within 1 hour of mixing. Throw away any unused liquid.
  • Take this medicine with food.

Measure the oral liquid or delayed-release oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup. You may hand wash and reuse the provided mixing cup and syringes.

This medicine works best when there is a constant amount in the blood. To help keep the amount constant, do not miss any doses. Also, it is best to take each dose at the same time every day. If you need help in planning the best time to take your medicine, check with your doctor.

Posaconazole oral liquid works differently than the delayed-release tablet or delayed-release oral liquid, even at the same dose. Do not switch from one form to another unless your doctor tells you to.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For prevention of fungus infections:
    • For oral dosage form (delayed-release tablets):
      • Adults and children 2 years of age and older weighing more than 40 kilograms (kg)—300 milligrams (mg) (three 100 mg delayed-release tablets) 2 times a day on the first day, then 300 mg once a day.
      • Children younger than 2 years of age or weighing 40 kg or less—Use and dose must be determined by your doctor.
    • For oral dosage form (suspension):
      • Adults and children 13 years of age and older—200 milligrams (mg) or 5 milliliters (mL) 3 times a day.
      • Children younger than 13 years of age—Use and dose must be determined by your doctor.
    • For oral dosage form (delayed-release suspension):
      • Adults and children 2 years of age and older—Dose is based on body weight and must be determined by your doctor.
        • Weighing 36 to 40 kilograms (kg)—240 milligrams (mg) or 8 milliliters (mL) 2 times a day on the first day, then 240 mg or 8 mL once a day.
        • Weighing 26 to less than 36 kg—210 mg or 7 mL 2 times a day on the first day, then 210 mg or 7 mL once a day.
        • Weighing 21 to less than 26 kg—180 mg or 6 mL 2 times a day on the first day, then 180 mg or 6 mL once a day.
        • Weighing 17 to less than 21 kg—150 mg or 5 mL 2 times a day on the first day, then 150 mg or 5 mL once a day.
        • Weighing 12 to less than 17 kg—120 mg or 4 mL 2 times a day on the first day, then 120 mg or 4 mL once a day.
        • Weighing 10 to less than 12 kg—90 mg or 3 mL 2 times a day on the first day, then 90 mg or 3 mL once a day.
      • Children younger than 2 years of age—Use and dose must be determined by your doctor.
  • For treatment of invasive aspergillosis:
    • For oral dosage form (delayed-release tablets):
      • Adults and children 13 years of age and older—300 milligrams (mg) (three 100 mg delayed-release tablets) 2 times a day on the first day, then 300 mg once a day for 6 to 12 weeks.
      • Children younger than 13 years of age—Use and dose must be determined by your doctor.
  • For initial treatment of oral candidiasis:
    • For oral dosage form (suspension):
      • Adults and children 13 years of age and older—100 milligrams (mg) or 2.5 milliliters (mL) 2 times a day on the first day, then 100 mg or 2.5 mL once a day for 13 days.
      • Children younger than 13 years of age—Use and dose must be determined by your doctor.
  • For treatment of oral candidiasis after failed treatment with itraconazole or fluconazole:
    • For oral dosage form (suspension):
      • Adults and children 13 years of age and older—400 milligrams (mg) or 10 milliliters (mL) 2 times a day.
      • Children younger than 13 years of age—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Do not take the delayed-release tablet if it has been more than 12 hours since you missed your last dose.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Portions of this document last updated: April 01, 2024

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