Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

  1. Black, tarry stools
  2. bleeding gums
  3. blood in the urine or stools
  4. blurred vision
  5. chest pain or tightness
  6. confusion
  7. cough
  8. decreased urine
  9. dizziness
  10. dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  11. drowsiness
  12. dry mouth
  13. fainting
  14. fast or irregular heartbeat
  15. fever or chills
  16. headache
  17. increased thirst
  18. lightheadedness
  19. loss of appetite
  20. muscle pain, cramps, spasms, or twitching
  21. nausea or vomiting
  22. nervousness
  23. numbness or tingling in the hands, feet, or lips
  24. pale skin
  25. pinpoint red spots on the skin
  26. pounding in the ears
  27. rapid, shallow breathing
  28. seizures
  29. slow heartbeat
  30. sneezing
  31. sore throat
  32. sweating
  33. trembling
  34. trouble breathing
  35. unusual bleeding or bruising
  36. unusual tiredness or weakness

Less common

  1. Bladder pain
  2. blue lips, fingernails, or skin
  3. bone pain
  4. chest discomfort
  5. cloudy urine
  6. coma
  7. decreased urine output
  8. difficult, burning, or painful urination
  9. fast, pounding, or irregular heartbeat or pulse
  10. frequent urge to urinate
  11. headache
  12. irregular, fast or slow, or shallow breathing
  13. irritability
  14. lower back or side pain
  15. muscle cramps in the hands, arms, feet, legs, or face
  16. restlessness
  17. stomach cramps or pain
  18. swelling of the face, feet, lower legs, ankles, or hands
  19. weakness or heaviness of the legs


  1. Severe pain in the chest
  2. sudden onset of severe breathing difficulty

Incidence not known

  1. Arm, back, or jaw pain
  2. blistering, peeling, or loosening of the skin
  3. bloating or swelling of the face, arms, hands, lower legs, or feet
  4. chest tightness or heaviness
  5. constipation
  6. cough or hoarseness
  7. dark-colored urine
  8. diarrhea
  9. difficulty with swallowing
  10. fever with or without chills
  11. general body swelling
  12. general feeling of tiredness or weakness
  13. greatly decreased frequency of urination or amount of urine
  14. high fever
  15. hives or skin rash
  16. indigestion
  17. joint or muscle pain
  18. large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  19. light-colored stools
  20. mood or mental changes
  21. noisy breathing
  22. nosebleeds
  23. pain with swallowing
  24. pains in the stomach, side, or abdomen, possibly radiating to the back
  25. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  26. rapid weight gain
  27. red skin lesions, often with a purple center
  28. red, irritated eyes
  29. sores, ulcers, or white spots on the lips or in the mouth
  30. stomach pain, continuing
  31. sweating
  32. swollen glands
  33. unexplained bleeding or bruising
  34. unusual weight gain or loss
  35. weight gain
  36. yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

  1. Feeling of warmth
  2. increased sweating
  3. redness of the face, neck, arms, and occasionally, upper chest

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  1. Agitation
  2. cold sweats
  3. cool, pale skin
  4. depression
  5. excess air or gas in the stomach or intestines
  6. flushed, dry skin
  7. fruit-like breath odor
  8. full feeling
  9. increased hunger
  10. increased thirst
  11. increased urination
  12. lack or loss of strength
  13. nightmares
  14. passing gas
  15. shakiness
  16. slurred speech
  17. white patches in the mouth or throat or on the tongue
  18. white patches with diaper rash

Incidence not known

  1. Abnormal dreams
  2. attack, assault, or force
  3. bad, unusual, or unpleasant (after) taste
  4. blindness
  5. blue-yellow color blindness
  6. change in taste
  7. continuing ringing or buzzing or other unexplained noise in the ears
  8. decreased interest in sexual intercourse
  9. decreased vision
  10. double vision
  11. dry eyes or skin
  12. eye pain
  13. feeling of constant movement of self or surroundings
  14. general feeling of discomfort or illness
  15. hair loss or thinning of the hair
  16. hearing loss
  17. hives or welts
  18. inability to have or keep an erection
  19. increased sensitivity of the skin to sunlight
  20. itching, redness, tearing, or other sign of eye irritation not present before use of this medicine or becoming worse during use
  21. lack of feeling or emotion
  22. loss in sexual ability, desire, drive, or performance
  23. pain in the testes
  24. pinpoint red or purple spots on the skin
  25. redness or other discoloration of the skin
  26. seeing, hearing, or feeling things that are not there
  27. sensation of spinning
  28. severe sunburn
  29. sleepiness or unusual drowsiness
  30. sugar in the urine
  31. swelling of the breasts or breast soreness in both females and males
  32. swelling or inflammation of the mouth
  33. trouble sleeping
  34. uncaring

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.