Before Using

Drug information provided by: Merative, Micromedex®

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of atidarsagene autotemcel injection in children. However, safety and efficacy have not been established in children with late juvenile MLD.

Geriatric

No information is available on the relationship of age to the effects of atidarsagene autotemcel injection in geriatric patients.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Abacavir
  • Abacavir Sulfate
  • Adenovirus Vaccine, Live
  • Amprenavir
  • Anthrax Vaccine Adsorbed
  • Atazanavir
  • Atazanavir Sulfate
  • Bacillus of Calmette and Guerin Vaccine, Live
  • Cabotegravir
  • Cholera Vaccine
  • Cholera Vaccine, Live
  • Cobicistat
  • Darunavir
  • Darunavir Ethanolate
  • Delavirdine
  • Delavirdine Mesylate
  • Dengue Tetravalent Vaccine, Live
  • Didanosine
  • Diphtheria Toxoid, Adsorbed
  • Dolutegravir
  • Dolutegravir Sodium
  • Doravirine
  • Ebola Zaire Vaccine, Live
  • Efavirenz
  • Elvitegravir
  • Emtricitabine
  • Enfuvirtide
  • Etravirine
  • Fosamprenavir
  • Fosamprenavir Calcium
  • Fostemsavir
  • Haemophilus B Vaccine
  • Hepatitis A Vaccine, Inactivated
  • Hepatitis B Vaccine
  • Human Papillomavirus Vaccine
  • Ibalizumab-uiyk
  • Indinavir
  • Indinavir Sulfate
  • Influenza Virus Vaccine
  • Influenza Virus Vaccine, Live
  • Japanese Encephalitis Virus Vaccine
  • Lamivudine
  • Lenacapavir
  • Lopinavir
  • Maraviroc
  • Measles Virus Vaccine, Live
  • Meningococcal Polysaccharide Vaccine
  • Meningococcal Vaccine
  • Mumps Virus Vaccine, Live
  • Nelfinavir
  • Nelfinavir Mesylate
  • Nevirapine
  • Pertussis Vaccine
  • Pneumococcal Vaccine
  • Pneumococcal Vaccine, Diphtheria Conjugate
  • Pneumococcal Vaccine Polyvalent
  • Poliovirus Vaccine, Inactivated
  • Poliovirus Vaccine, Live
  • Rabies Vaccine
  • Raltegravir
  • Raltegravir Potassium
  • Rilpivirine
  • Rilpivirine Hydrochloride
  • Ritonavir
  • Rotavirus Vaccine, Live
  • Rubella Virus Vaccine, Live
  • Saquinavir
  • Saquinavir Mesylate
  • SARS-COV-2 (COVID-19) Vaccine, Adenovirus 26 Vector (Janssen)
  • SARS-COV-2 (COVID-19) Vaccine, mRNA (Moderna)
  • SARS-COV-2 (COVID-19) Vaccine, mRNA (Pfizer)
  • SARS-COV-2 (COVID-19) Vaccine, Protein Subunit, Adjuvanted (Novavax)
  • SARS-COV-2 (COVID-19) Vaccine, Protein Subunit, Adjuvanted (Sanofi)
  • Smallpox Monkeypox Vaccine, Live Non-Replicating
  • Smallpox Vaccine
  • Stavudine
  • Tenofovir
  • Tenofovir Alafenamide
  • Tenofovir Disoproxil Fumarate
  • Tetanus Toxoid
  • Tick-Borne Encephalitis Vaccine
  • Tipranavir
  • Typhoid Vaccine
  • Typhoid Vaccine, Live
  • Typhoid Vi Polysaccharide Vaccine
  • Varicella Virus Vaccine
  • Varicella Virus Vaccine, Live
  • Yellow Fever Vaccine
  • Zalcitabine
  • Zidovudine
  • Zoster Vaccine, Live

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Allergy to dimethyl sulfoxide (DMSO), history of—Use with caution. May increase the risk of an allergic reaction.
  • Kidney disease or
  • Liver disease—Use with caution. This medicine has not been studied in patients with these conditions.

Portions of this document last updated: May 01, 2024

Copyright: © Merative US L.P. 1973, 2024. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.