精神病与心理科

以下为当前的临床试验。

按院区、状态和其他条件筛选该研究列表。

1. Magnetic Resonance Elastography of Dementia

   Rochester, Minn.

   The purpose of this study is to develop and test the effectiveness of an investigational imaging technique called magnetic resonance elastography (MRE) to measure the stiffness (mechanical properties) of tissues.

2. Advanced Care Planning in Dementia

   Jacksonville, Fla.

   The goal of this study is to gain a better understanding of the status of advanced care planning among caregivers of patients with dementia and examine how this differs by race and disease stage.

3. A Study Evaluating the Prevalence, Incidence and Predictors for Development of the Impulse Control Disorders in Patients with Prolactinomas Treated with Dopamine Agonist Therapy

   Rochester, Minn., Jacksonville, Fla.

   The purpose of this study is to establish incidence and prevalence of Impulse Control Disorders (ICDs) in patients with prolactinomas treated with dopamine agonists (DA), to determine the predictors of ICD development, and to establish a predictor scoring system that could be subsequently validated and applied prior to initiation of DA.

4. A Study to Evaluate Visually Inspired Patient Education Material on Willingness to Pursue Radiation Therapy

   Scottsdale/Phoenix, Ariz.

   The purpose of this study is to measure how patient anxiety changes using a validated patient reported outcome measure, to measure radiotherapy completion rates in the American Indian/Alaska Native (AI/AN) community, and to measure patient perception of information received using a validated patient reported outcome measure.

    

    

5. A Study to Evaluate AAV8-human Cocaine Hydrolase to Treat Cocaine Use Disorder

   Rochester, Minn.

   The purpose of this study is to see if an experimental agent, when given to subjects who wish to abstain from cocaine, will decrease their craving for cocaine and prevent them from relapsing and returning to cocaine use.  This experimental agent is called AAV8-hCocH; and it is a gene modified viral vector.  We want to determine the safety of its use in adults who have a cocaine use disorder in sustained remission.  

6. Social Media Intervention to Promote Smoking Treatment Utilization and Cessation among Alaska Native Smokers

   Rochester, Minn.

   The purpose of this study is to develop and pilot test a culturally relevant, Facebook delivered intervention to promote smoking treatment uptake and cessation among Alaska Native (AN) smokers.

   Learn more about this study.

    

    

7. A Prospective Registry for Patients with REM Sleep Behavior Disorder and Polysomnographic REM Sleep without Atonia and Controls

   Rochester, Minn.

   The purpose of this study is to follow patients with REM sleep behavior disorder (RBD) over time and learn which types of RBD patients may be at risk of developing other diseases.

8. 8 Week Multi-site Study of MYDAYIS® for Bipolar Depression

   Rochester, Minn., Austin, Minn., Eau Claire, Wis.

   The purpose of this study is to assess the effectiveness and safety of MYDAYIS® as an augmentation agent for bipolar depression.

9. ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

   Rochester, Minn., Jacksonville, Fla.

   The purpose of this study is to evaluate sporadic (s-) and familial (f-) frontotemporal lobar degeneration (FTLD) patients and asymptomatic family members of f-FTLD patients, characterizing the cohorts longitudinally and informing clinical trial design.  FTLD is a neurodegenerative disorder of the nervous system which there are no approved treatments or cures.

   The study has two arms: a “longitudinal arm” involving a comprehensive assessment of clinical, functional, imaging, and biofluid data collection, and a “biofluid-focused arm” involving limited clinical data to accompany biospecimen collection.

10. Early Naturalistic Hands-on Autism Caregiver Training

    Rochester, Minn.

    The purpose of this study is to pilot test the ENHANCE intervention to evaluate methodology, feasibility based on caregiver input, and preliminary caregiver satisfaction. The primary outcomes will be feedback from parents, participant completion/atrition rates, the interventionist study log, and interventionist/caregiver/fidelity. Second, we aim to examine preliminary impact of the naturalistic intervention on child social communication and repetitive behavior in order to estimate clinically meaningful change for future research studies.