Vinaya Simha, M.B.B.S., M.D.
Endocrinologist
Internist
Himes CP, Ganesh R, Wight EC,
Simha V
, Liebow M. Perioperative Evaluation and Management of Endocrine Disorders. Mayo Clin Proc. 2020 Dec; 95 (12):2760-2774 Epub 2020 Nov 06
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Simha V
. Management of hypertriglyceridemia. BMJ. 2020 Oct 12; 371:m3109
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Brown SA, Beck RW, Raghinaru D, Buckingham BA, Laffel LM, Wadwa RP, Kudva YC, Levy CJ, Pinsker JE, Dassau E, Doyle FJ 3rd, Ambler-Osborn L, Anderson SM, Church MM, Ekhlaspour L, Forlenza GP, Levister C,
Simha V
, Breton MD, Kollman C, Lum JW, Kovatchev BP, iDCL Trial Research Group. Glycemic Outcomes of Use of CLC Versus PLGS in Type 1 Diabetes: A Randomized Controlled Trial. Diabetes Care. 2020 Aug; 43 (8):1822-1828 Epub 2020 May 29
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Simha V
, Shah P. Perioperative Glucose Control in Patients With Diabetes Undergoing Elective Surgery. JAMA. 2019 Jan 29; 321 (4):399-400
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Simha V
, Qin S, Shah P, Smith BH, Kremers WK, Kushwaha S, Wang L, Pereira NL. Sirolimus Therapy Is Associated with Elevation in Circulating PCSK9 Levels in Cardiac Transplant Patients. J Cardiovasc Transl Res. 2017 Feb; 10 (1):9-15 Epub 2016 Dec 27
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Moriarty PM, Parhofer KG, Babirak SP, Cornier MA, Duell PB, Hohenstein B, Leebmann J, Ramlow W, Schettler V,
Simha V
, Steinhagen-Thiessen E, Thompson PD, Vogt A, von Stritzky B, Du Y, Manvelian G. Alirocumab in patients with heterozygous familial hypercholesterolaemia undergoing lipoprotein apheresis: the ODYSSEY ESCAPE trial. Eur Heart J. 2016 Dec 21; 37 (48):3588-3595 Epub 2016 Aug 29
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Simha V
, Kudva YC. HDL Cholesterol Story Is Dead: Long Live HDL! Diabetes 2016 Oct; 65 (10):2826-8
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Moriarty PM, Parhofer KG, Babirak SP, deGoma E, Duell PB, Hohenstein B, Ramlow W,
Simha V
, Steinhagen-Thiessen E, Thompson PD, Vogt A, von Stritzky B, Du Y, Manvelian G. Alirocumab in patients with heterozygous familial hypercholesterolemia undergoing lipoprotein apheresis: Rationale and design of the ODYSSEY ESCAPE trial. J Clin Lipidol. 2016 May-Jun; 10 (3):627-34 Epub 2016 Feb 18
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Musso C, Major ML, Andres E,
Simha V
. Metreleptin Treatment in Three Patients with Generalized Lipodystrophy. Clin Med Insights Case Rep. 2016; 9:123-127 Epub 2017 Jan 05
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Simha V
. Drug-induced dyslipidemia Contemporary Endocrinology. 2015; 1:267-86.
Lopez-Jimenez F,
Simha V
, Thomas RJ, Allison TG, Basu A, Fernandes R, Hurst RT, Kopecky SL, Kullo IJ, Mulvagh SL, Thompson WG, Trejo-Gutierrez JF, Wright RS. A summary and critical assessment of the 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular disease risk in adults: filling the gaps. Mayo Clin Proc. 2014 Sep; 89 (9):1257-78 Epub 2014 Aug 12
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Simha V
. Metreleptin for metabolic disorders associated with generalized or partial lipodystrophy. Expert Rev. Endocrinol. Metab. 2014; 9(3):205-12.
Nelson MD, Victor RG, Szczepaniak EW,
Simha V
, Garg A, Szczepaniak LS. Cardiac steatosis and left ventricular hypertrophy in patients with generalized lipodystrophy as determined by magnetic resonance spectroscopy and imaging. Am J Cardiol. 2013 Oct 1; 112(7):1019-24. Epub 2013 Jun 22.
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Ahmad Z, Subramanyam L, Szczepaniak L,
Simha V
, Adams-Huet B, Garg A. Cholic acid for hepatic steatosis in patients with lipodystrophy: a randomized, controlled trial. Eur J Endocrinol. 2013 May; 168(5):771-8. Epub 2013 Apr 15.
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Simha V
, Mahmood M, Ansari M, Spellman CW, Shah P. Effect of vitamin D replacement on insulin sensitivity in subjects with vitamin D deficiency. J Investig Med. 2012 Dec; 60: (8)1214-8.
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Simha V
, Subramanyam L, Szczepaniak L, Quittner C, Adams-Huet B, Snell P, Garg A. Comparison of efficacy and safety of leptin replacement therapy in moderately and severely hypoleptinemic patients with familial partial lipodystrophy of the Dunnigan variety. J Clin Endocrinol Metab. 2012 Mar; 97(3):785-92. Epub 2011 Dec 14.
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Shrikanth V, Vanderheiden A,
Simha V
. Spontaneous intracerebral hemorrhage associated with ingestion of isometheptine containing anti-migraine medication. Clin Neurol Neurosurg. 2011 Feb; 113(2):167-9. Epub 2010 Nov 13.
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Shastry S,
Simha V
, Godbole K, Sbraccia P, Melancon S, Yajnik CS, Novelli G, Kroiss M, Garg A. A novel syndrome of mandibular hypoplasia, deafness, and progeroid features associated with lipodystrophy, undescended testes, and male hypogonadism. J Clin Endocrinol Metab. 2010 Oct; 95(10):E192-7. Epub 2010 Jul 14.
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Subramanyam L,
Simha V
, Garg A. Overlapping syndrome with familial partial lipodystrophy, Dunnigan variety and cardiomyopathy due to amino-terminal heterozygous missense lamin A/C mutations. Clin Genet. 2010 Jul; 78(1):66-73. Epub 2009 Dec 22.
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Ahmed K, Rao S,
Simha V
. Antineutrophil cytoplasmic antibody-positive vasculitis in a patient with graves disease: cross-reaction between propylthiouracil and methimazole. Endocr Pract. 2010 May-Jun; 16(3):449-51.
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Garg A, Subramanyam L, Agarwal AK,
Simha V
, Levine B, D'Apice MR, Novelli G, Crow Y. Atypical progeroid syndrome due to heterozygous missense LMNA mutations. J Clin Endocrinol Metab. 2009 Dec; 94(12):4971-83. Epub 2009 Oct 29.
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Simha V
, Garg A. Inherited lipodystrophies and hypertriglyceridemia. Curr Opin Lipidol. 2009 Aug; 20(4):300-8.
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Keller J, Subramanyam L,
Simha V
, Gustofson R, Minjarez D, Garg A. Lipodystrophy: an unusual diagnosis in a case of oligomenorrhea and hirsutism. Obstet Gynecol. 2009 Aug; 114(2 Pt 2):427-31.
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Simha V
, Agarwal AK, Aronin PA, Iannaccone ST, Garg A. Novel subtype of congenital generalized lipodystrophy associated with muscular weakness and cervical spine instability. Am J Med Genet A. 2008 Sep 15; 146A(18):2318-26.
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Simha V
. Dietary carbohydrates and risk of type 2 diabetes: are rice eaters doomed? Natl Med J India. 2008 Mar-Apr; 21(2):80-1.
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O'Neill B,
Simha V
, Kotha V, Garg A. Body fat distribution and metabolic variables in patients with neonatal progeroid syndrome. Am J Med Genet A. 2007 Jul 1; 143A(13):1421-30.
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Garg A,
Simha V
. Update on dyslipidemia. J Clin Endocrinol Metab. 2007 May; 92(5):1581-9.
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Shah M,
Simha V
, Garg A. Review: long-term impact of bariatric surgery on body weight, comorbidities, and nutritional status. J Clin Endocrinol Metab. 2006 Nov; 91(11):4223-31. Epub 2006 Sep 5
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Simha V
, Garg A. Lipodystrophy: lessons in lipid and energy metabolism. Curr Opin Lipidol. 2006 Apr; 17(2):162-9.
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Simha V
, Garg A. Phenotypic heterogeneity in body fat distribution in patients with congenital generalized lipodystrophy caused by mutations in the AGPAT2 or seipin genes. J Clin Endocrinol Metab. 2003 Nov; 88(11):5433-7.
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Agarwal AK,
Simha V
, Oral EA, Moran SA, Gorden P, O'Rahilly S, Zaidi Z, Gurakan F, Arslanian SA, Klar A, Ricker A, White NH, Bindl L, Herbst K, Kennel K, Patel SB, Al-Gazali L, Garg A. Phenotypic and genetic heterogeneity in congenital generalized lipodystrophy. J Clin Endocrinol Metab. 2003 Oct; 88(10):4840-7.
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Simha V
, Agarwal AK, Oral EA, Fryns JP, Garg A. Genetic and phenotypic heterogeneity in patients with mandibuloacral dysplasia-associated lipodystrophy. J Clin Endocrinol Metab. 2003 Jun; 88(6):2821-4.
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Simha V
, Szczepaniak LS, Wagner AJ, DePaoli AM, Garg A. Effect of leptin replacement on intrahepatic and intramyocellular lipid content in patients with generalized lipodystrophy. Diabetes Care. 2003 Jan; 26(1):30-5.
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Simha V
, Zerwekh JE, Sakhaee K, Garg A. Effect of subcutaneous leptin replacement therapy on bone metabolism in patients with generalized lipodystrophy. J Clin Endocrinol Metab. 2002 Nov; 87(11):4942-5.
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Oral EA,
Simha V
, Ruiz E, Andewelt A, Premkumar A, Snell P, Wagner AJ, DePaoli AM, Reitman ML, Taylor SI, Gorden P, Garg A. Leptin-replacement therapy for lipodystrophy. N Engl J Med. 2002 Feb 21; 346(8):570-8.
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Simha V
, Garg A. Body fat distribution and metabolic derangements in patients with familial partial lipodystrophy associated with mandibuloacral dysplasia. J Clin Endocrinol Metab. 2002 Feb; 87(2):776-85.
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