Mayo Clinic Healthcare commonly sees people with:

• A strong family history of gastrointestinal or other cancers, including inherited cancer syndromes, such as:
  • Cowden syndrome.
  • Familial adenomatous polyposis (FAP).
  • Hereditary nonpolyposis colorectal cancer, also known as HNPCC or Lynch syndrome.
  • Juvenile polyposis syndrome.
  • MUTYH-associated polyposis.
  • Peutz-Jeghers syndrome.
• Known or suspected gastrointestinal cancers, such as stomach, small bowel, colon or rectal cancer.
• Known or suspected gastrointestinal precancers, called colorectal polyps.
• Benign or malignant gastrointestinal cancers that require advanced endoscopic or surgical management.
• Higher than average risk of gastrointestinal cancer based on:
  • Family history of gastrointestinal cancer or polyposis, including heritable syndromes.
  • Past personal history of gastrointestinal cancer or precancer.
  • Long-standing ulcerative colitis or Crohn's disease.
• Symptoms or signs of gastrointestinal cancer, such as persistent upper or lower gastrointestinal bleeding, change in stool pattern and lower abdominal pain; stool blood test results outside of the standard range; iron deficiency or anaemia; and weight loss that is not intentional. These cancers include:
  • Anal cancer.
  • Cancer of the appendix.
  • Carcinoid tumours, also called neuroendocrine tumours.
  • Cronkhite-Canada syndrome.
  • Fundic gland polyp dysplasia.
  • Gastrointestinal stromal tumours (GISTs).
  • Gastric intestinal metaplasia.
  • Lymphoma of colon or rectum.
  • Melanoma of the GI tract.
  • Uncommon neoplasms of the stomach, small intestine, colon or rectum.

Read more about Mayo Clinic's Cancer Center in the U.S.