Mayo Clinic's approach


The Transgender and Intersex Specialty Care Clinic (TISCC) provides integrated medical, psychosocial and surgical intervention to individuals with gender dysphoria or incongruence and to those with disorders of sexual development. The team includes providers from various specialties, including endocrinology, pediatric endocrinology, social work, psychiatry, psychology, voice therapy, gynecology and plastic surgery.


Treatments offered include:

  • Mental health assessment and management
  • Hormonal therapy and monitoring
  • Assistance with social and legal issues and referrals to community resources
  • Fertility preservation
  • Sexually transmitted infection screening and preexposure prophylaxis (PrEP)
  • Voice therapy
  • Electrolysis and laser hair removal
  • Hair transplant
  • Gynecologic care for trans men
  • Chaplain services
  • Feminizing surgical procedures:
    • Breast augmentation
    • Facial feminization
    • Body contouring procedures
    • Orchiectomy
    • Tracheal shave
    • Penile inversion vaginoplasty
  • Masculinizing surgical procedures:
    • Breast reduction/chest masculinization
    • Body contouring procedures
    • Hysterectomy/oophorectomy

Before you start treatment, you'll meet with at least one member of the TISCC medical team, a doctor or a nurse practitioner, and a member of the TISCC mental health team, a social worker, a psychologist or a psychiatrist. You'll have a complete medical evaluation to make sure that your treatment risks are identified and addressed. Evaluation of your mental health ensures that any mood or mental health concerns are reasonably well managed before treatment begins.

Each person is different. Your providers will look at your specific case in order to come up with the best recommendations for you. Your health care team will work with you during your treatment and make sure your expectations are realistic. Your team wants to make sure your goals are being met, any risks are reduced and managed, and your questions are answered.


Mayo Clinic specialists are committed to providing the latest, most comprehensive treatment options for gender dysphoria. Your Mayo Clinic specialist's advice about the best treatment for you will be based on expert knowledge of and experience with all treatment options for gender dysphoria.

Expertise and rankings

At Mayo Clinic, endocrinologists, psychiatrists, psychologists, nurse practitioners, social workers and surgeons work together to provide exactly the care you need.

Having all of this expertise in a single place, focused on you, means that you're not just getting one opinion — your care is discussed among the team, your test results are available quickly, your appointments are scheduled in coordination and highly specialized experts are all working together to determine what's best for you.

More information about billing and insurance:

Mayo Clinic in Arizona, Florida and Minnesota

Mayo Clinic Health System

Sept. 28, 2019
  1. Coleman, et al. Standards of Care for the Health of Transsexual, Transgender and Gender Nonconforming People. 7th ver. World Professional Association for Transgender Health; 2012. Accessed March 22, 2019.
  2. Tangpricha V, et al. Transgender women: Evaluation and management. Accessed March 22, 2019.
  3. Erickson-Schroth L, ed. Trans Bodies, Trans Selves: A Resource for the Transgender Community. Oxford University Press; 2014.
  4. Hancock AB, et al. Transgender voice and communication treatment: A retrospective chart review of 25 cases. International Journal of Language and Communication Disorders. 2013; doi: 10.1111/j.1460-6984.2012.00185.x.
  5. Meister J, et al. Pitch elevation in male-to-female transgender persons — the Wurzburg approach. Journal of Voice. 2017;31:244.
  6. Van Damme S, et al. The effectiveness of pitch-raising surgery in male-to-female transsexuals: A systematic review. Journal of Voice. 2017; doi: 10.1016/j.jvoice.2016.04.002.
  7. Orbelo DM (expert opinion). Mayo Clinic. July 30, 2019.
  8. Mills M, et al. The Voice Book for Trans and Non-Binary People: A Practical Guide to Creating and Sustaining Authentic Voice and Communication. Jessica Kingsley Publishers; 2017.
  9. Song TE, et al. Transgender phonosurgery: A systematic review and meta-analysis. Otolaryngology — Head and Neck Surgery. 2017; doi: 10.1177/0194599817697050.
  10. More E, et al. Comparison of cricothyroid approximation and glottoplasty for surgical voice feminization in male-to-female transsexuals. The Layrngoscope. 2018; doi: 10.1002/lary.27172.

Voice feminizing therapy and surgery