Mayo Clinic researchers in the Transplant Center conduct ongoing studies and clinical trials in improving surgical procedures, improving outcomes and caring for people who need transplants. Researchers also study alternative therapies for people who might be able to use an alternative to a heart transplant.

Areas of research include:

  • Cardiac regenerative therapies in cardiac regeneration research
  • Genetics and potential treatments for hypoplastic left heart syndrome, a rare congenital heart defect
  • Biomarkers and genetics to individualize therapy
  • New or improved surgical procedures
  • Selecting and treating heart transplant recipients
  • Therapeutic approaches to prolong graft survival
  • Managing immunosuppressive medications after transplant
  • New immunosuppressant medications
  • Outcomes after heart transplants
  • Blood test to monitor for rejection
  • Ventricular assist devices
  • Alternative therapies for people who may not need heart transplants
  • Wellness coaching for caregivers and transplant recipients
  • Transplanting living organs from one species to another (xenotransplantation)
  • Gene therapy


See a list of publications about heart transplant by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.