If a healthcare professional discovers high blood protein during a test, more tests can help find if there is a condition that is causing it.

A total protein test may be done. Other, more-specific tests, including serum protein electrophoresis (SPEP), can help find the exact source, such as the liver or bone marrow. These tests also can identify the specific protein type involved in your high blood protein levels. Your healthcare professional may order an SPEP if a bone marrow disease is suspected.