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  1. Clinical Study to Evaluate Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy

    This is a multicenter, international, double-blind study of the administration of mavacamten in participants with symptomatic obstructive HCM (oHCM).

  2. A Study to Evaluate Whether or Not Selexipag is Effective and Safe in Patients with Chronic Thromboembolic Pulmonary Hypertension when the Disease is Inoperable or Persistent/Recurrent After Surgery - Mayo Clinic

    About this study. The primary objective of this study is to evaluate the effect of selexipag on pulmonary vascular resistance (PVR) versus placebo in ...

  3. A Study of MK-1026 in Patients with Selected Hematologic Malignancies - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  4. Heart Sounds Measurement Using The Wearable Cardioverter Defibrillator In Hospitalized Acute Heart Failure Patients - Mayo Clinic

    A study to evaluate the changes in heart sounds measurements recorded by the LifeVest® Wearable Cardioverter Defibrillator (WCD) during the medical treatment of ...

  5. Study of MK-8242 Alone and in Combination with Cytarabine in Participants with Acute Myelogenous Leukemia (P07649) - Mayo Clinic

    Arm B is for participants with recurrent AML following an initial complete remission (CR) or CR with incomplete marrow recovery (CRi) of 6 to 12 months duration ...

  6. CTX131 in Relapsed/Refractory Hematologic Malignancies - Mayo Clinic

    The purpose of this study is to evaluate the safety, efficacy, pharmacokinetics (PK), and pharmacodynamic effects of CTX131 in adult study subjects with ...

  7. Alternate Doses and Dosing Schedules of Belantamab Mafodotin for the Treatment of Triple-Class Recurrent and/or Refractory Multiple Myeloma - Mayo Clinic

    The purpose of this study is to assess the 24-week grade 3/4 keratopathy-free rate of an alternative dose/dosing schedule for belantamab mafodotin in patients ...

  8. A Study to Evaluate the Safety and Tolerability of DCC-2618 in Patients with Advanced Malignancies - Mayo Clinic

    This is a Phase 1, open-label, first-in-human (FIH) dose-escalation study designed to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics ...

  9. A Study of XmAb ®18087 in Subjects With NET and GIST - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  10. Monogenic Risk - eMERGE Genome Informed Risk Assessment - Mayo Clinic Research

    The eMERGE Genome Informed Risk Assessment study at Mayo Clinic estimates adult participants' risk of getting certain conditions from rare variants in a ...