/rss/research-newsFind news related to research at Mayo Clinic.en-USShutterstock ROCHESTER, Minn. — Researchers at Mayo Clinic have uncovered a previously hidden step in how the immune system prepares to fight cancer, a discovery that could help scientists develop more effective and longer-lasting cancer immunotherapies. Published in Nature Communications, the study found that some cancer-fighting immune cells begin preparing for their role much earlier than previously believed — while they are still maturing in the thymus, an organ behind the breastbone that plays a…https://newsnetwork.mayoclinic.org/?p=416088Wednesday, June 24, 2026Getty Study uncovers structure of protein that helps cells communicate, a potential drug target ROCHESTER, Minn. — After nearly four decades of research, Mayo Clinic scientists have revealed the molecular structures of protein kinase C beta (PKCβ), a key protein linked to cancer and neurological diseases. The findings, published in Nature Communications, provide the first detailed view of how the protein works and how the breast cancer drug endoxifen can target this protein. PKCs are…https://newsnetwork.mayoclinic.org/?p=416084Tuesday, June 23, 2026At Mayo Clinic, neuroscientists are seeking to understand — and ultimately restore — brain function through advanced computational tools, neuromodulation technologies and multidisciplinary collaboration. Gelareh Zadeh, M.D., Ph.D. These new efforts are led by Gelareh Zadeh, M.D., Ph.D., a neurosurgeon and scientist. Dr. Zadeh specializes in neuro-oncology and has clinical expertise in treating brain tumors such as gliomas and meningiomas. Her research focuses on the molecular and genomic landscape of these tumors to advance precision…https://newsnetwork.mayoclinic.org/?p=416056Monday, June 22, 2026The BAC on routine screening mammograms is shown in red. AI was used to help clinicians measure and quantify it, creating an opportunity to assess heart disease risk during a test many women already receive without additional radiation or testing. A routine mammogram may do more than detect breast cancer, it also could help identify early signs of heart disease. Heart disease is the leading cause of death among women, responsible for 1 in 3…https://newsnetwork.mayoclinic.org/?p=416024Wednesday, June 17, 2026Mayo Clinic researchers have identified a previously unrecognized way the kidneys regulate water balance — an advance that could lead to improved treatments for polycystic kidney disease (PKD) and other disorders.https://newsnetwork.mayoclinic.org/?p=413549Tuesday, June 16, 2026One of the most detailed maps to date of meningioma — the most common brain tumor in adults — reveals how the tumor's surrounding environment helps drive disease behavior and patient outcomes, according to new research from Mayo Clinic.https://newsnetwork.mayoclinic.org/?p=415616Tuesday, June 9, 2026ROCHESTER, Minn. — Mayo Clinic researchers and collaborators have shown that an artificial intelligence (AI) tool can analyze routine pathology slides to help clinicians classify meningiomas, the most common primary brain tumor in adults, and better understand a patient’s risk of tumor recurrence. The study, published in The Lancet Digital Health, demonstrates that deep learning models can support the extraction of molecular and prognostic information from standard hematoxylin and eosin, or H&E, slides — the…https://newsnetwork.mayoclinic.org/?p=415769Monday, June 8, 2026PHOENIX — In a study published in the Liver Transplantation journal by the American Association for the Study of Liver Diseases, Mayo Clinic researchers found that a new proactive treatment protocol for alcohol use disorder after liver transplant resulted in a 0% heavy alcohol relapse rate among patients who followed the protocol, compared with a historical relapse rate of approximately 25%. "The results were greater than we expected," says Channa Jayasekera, M.D., Mayo Clinic transplant…https://newsnetwork.mayoclinic.org/?p=415735Wednesday, June 3, 2026PHOENIX — An experimental drug combination may help overcome treatment resistance in advanced kidney cancer, according to early results from a first-in-human clinical trial led by Mayo Clinic researchers. The study evaluated the investigational drug darlifarnib in combination with the targeted therapy cabozantinib, a standard treatment for clear cell renal cell carcinoma (ccRCC), the most common type of kidney cancer. Among patients whose disease had progressed despite prior treatment, 44% responded to the combination therapy,…https://newsnetwork.mayoclinic.org/?p=415648Tuesday, June 2, 2026Getty Images JACKSONVILLE, Fla. — Hormone therapy use among women in the U.S. remains low, even though it's an effective treatment for many menopause symptoms, according to a new Mayo Clinic study published in Mayo Clinic Proceedings. Menopause affects more than 1 million women each year in the U.S., and up to 75% experience symptoms such as hot flashes and night sweats that can last for years. Yet researchers found that use of menopausal hormone…https://newsnetwork.mayoclinic.org/?p=415627Monday, June 1, 2026Shutterstock ROCHESTER, Minn. — Mayo Clinic Comprehensive Cancer Center researchers will present more than 30 studies at the 2026 American Society of Clinical Oncology (ASCO) Annual Meeting, highlighting advances in precision oncology, early cancer detection, artificial intelligence (AI) and personalized cancer care. The meeting will be held May 29–June 2 at the McCormick Place Convention Center in Chicago. Featured research includes biomarker-driven treatments for bladder and lung cancers, new approaches for triple-negative breast cancer, multicancer…https://newsnetwork.mayoclinic.org/?p=415387Wednesday, May 27, 2026Each year, about 90,000 people in the U.S. are diagnosed with a brain tumor, including roughly 25,000 with cancerous tumors. These tumors are especially challenging because in the brain, even small changes can affect critical functions like movement, speech and memory. Across Mayo Clinic's campuses in Rochester, Arizona and Florida, researchers are advancing the understanding of brain tumor biology, improving diagnostic precision and developing new treatment approaches to support timely, personalized care. Reading a brain…https://newsnetwork.mayoclinic.org/?p=415022Monday, May 18, 2026As global attention intensifies around neurodegenerative diseases such as Alzheimer's disease, frontotemporal dementia (FTD), progressive supranuclear palsy (PSP), and corticobasal degeneration (CBD), Mayo Clinic researchers are helping drive discoveries that could improve how these conditions are diagnosed and understood. At the recent Tau Global Conference in Washington, D.C., Mayo Clinic researchers Dennis Dickson, M.D., and Melissa Murray, Ph.D., were recognized for their scientific contributions that have advanced research into tau-related neurodegenerative diseases, characterized by abnormal…https://newsnetwork.mayoclinic.org/?p=414905Friday, May 15, 2026 Cui Tao, Ph.D. Artificial intelligence (AI) and automation are enabling researchers to advance discoveries into patient care faster and with greater precision, opening new ways to address complex needs in medicine. "With AI, they're now able to ask and answer questions that they were not able to answer before," says Cui Tao, Ph.D., a professor of Biomedical Informatics and the Nancy Peretsman and Robert Scully Chair of Artificial Intelligence and Informatics at Mayo Clinic.   Researchers are also using AI to identify clinical…https://newsnetwork.mayoclinic.org/?p=414739Friday, May 15, 2026A new era of medicine is emerging at Mayo Clinic — one that finds disease before symptoms appear  ROCHESTER, Minn. — When Mayo Clinic researchers sequenced the genomes of 484 seemingly healthy adults, they found that about 13% carried a serious, previously unrecognized genomic risk — conditions those patients did not know about and that standard care would likely miss. Nearly all participants, 98.6%, had at least one genetic finding, and for most, the results called for monitoring.…https://newsnetwork.mayoclinic.org/?p=414078Thursday, May 14, 2026ROCHESTER, Minn. — Mayo Clinic researchers have identified an immune-regulating molecule that may help explain why some patients with inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis, do not respond to commonly used therapies. The findings, published in Cell Reports, describe a previously uncharacterized role for the molecule ST8Sia6 in regulating immune activity in the gut. In preclinical models, researchers found that the absence of ST8Sia6 led to a marked increase in inflammatory…https://newsnetwork.mayoclinic.org/?p=414628Wednesday, May 13, 2026May is Stroke Awareness Month, and knowing the signs and symptoms of stroke can save your life or the life of someone you care about. Stroke can happen suddenly, and every second counts when it comes to getting treatment. Doctors at Mayo Clinic say remembering a simple acronym — B.E.F.A.S.T. — can help you recognize the warning signs of stroke and act quickly. [chCustomLinkedDataJson] { "@context": "http://schema.org", "@type": "VideoObject", "name": "Mayo Clinic Minute – B.E.F.A.S.T.…https://newsnetwork.mayoclinic.org/?p=414564Tuesday, May 12, 2026ROCHESTER, Minn. — Mayo Clinic and Stanford Medicine researchers have developed the first blood test to map the complex ecosystem surrounding cancer cells, offering a more accurate way to predict which patients will benefit from immunotherapy. Their study's findings, published in Nature, represent a major advance in precision oncology and could help guide treatment decisions across multiple cancer types and treatments. Aadel Chaudhuri, M.D., Ph.D., speaks with a patient and her husband in a hospital…https://newsnetwork.mayoclinic.org/?p=414250Wednesday, May 6, 2026In a laboratory at Mayo Clinic, a machine that looks strikingly similar to a desktop printer is quietly reshaping the future of dermatology. Instead of ink, it dispenses living human cells. Instead of paper, it builds tissue — layer by layer — replicating one of the body's most complex organs: skin. For Saranya Wyles, M.D., Ph.D., a dermatologist and researcher at Mayo Clinic, the journey into 3D bioprinting began not with an ambitious plan to reinvent tissue engineering, but with a practical problem. Her team needed a better way to test new therapies.https://newsnetwork.mayoclinic.org/?p=413103Tuesday, May 5, 2026Getty Images ROCHESTER, Minn. — Research from Mayo Clinic is helping refine how multiple myeloma is diagnosed and treated, with findings that support more personalized therapies and identify promising immunotherapy strategies for aggressive forms of the disease. The research led by Sikander Ailawadhi, M.D., Shaji Kumar, M.D., Akhilesh Pandey, M.D., Ph.D., and Richard Kandasamy, Ph.D. in the Mayo Clinic Comprehensive Cancer Center, focuses on tailoring treatment based on disease biology and improving outcomes for patients…https://newsnetwork.mayoclinic.org/?p=414127Monday, May 4, 2026