<?xml version="1.0" encoding="utf-8"?><rss version="2.0"><channel><title>Mayo Clinic Research news and Discovery's Edge</title><link>/rss/research-news</link><description>Find news related to research at Mayo Clinic.</description><language>en-US</language><item><title>Mayo Clinic Minute: Early screening and treatment advances improve prostate cancer outcomes</title><description>Prostate cancer is one of the most common cancers in men, and finding it early can expand treatment options, including highly precise radiation that targets the tumor while protecting nearby tissue. Watch: The Mayo Clinic Minute https://www.youtube.com/watch?v=dYWRfx4zNg4 Journalists: Broadcast-quality video (1:00) is in the downloads at the end of this post.&amp;nbsp;Please courtesy: "Mayo Clinic News Network." Read the&amp;nbsp;script. Screening for prostate cancer can start with a blood test. A prostate-specific antigen, or PSA, test measures&amp;hellip;</description><link>https://newsnetwork.mayoclinic.org/?p=417658</link><pubDate>Wednesday, October 7, 2026</pubDate></item><item><title>Mayo Clinic Minute: Seeing glioblastoma more clearly could improve how it's treated</title><description>What doctors can't see can make glioblastoma especially difficult to treat.&amp;nbsp; This aggressive brain cancer can extend beyond what's visible on a standard MRI, making it difficult to precisely target treatment. Just 5% to 7% of patients survive five years after diagnosis.&amp;nbsp; Mayo Clinic researchers are studying advanced imaging techniques designed to bring more of the tumor into view and potentially give care teams a better-defined target.&amp;nbsp; "We're trying to develop and improve treatments that&amp;hellip;</description><link>https://newsnetwork.mayoclinic.org/?p=418253</link><pubDate>Tuesday, October 6, 2026</pubDate></item><item><title>High school student's AI-powered cancer research leads to discovery at Mayo Clinic </title><description>"Alan Alwakeel (left), SPARK scholar, works on research in the lab with a Mayo Clinic research scientist. Long before he set foot in a research lab, Alan Alwakeel was already asking big questions about medicine, technology and how to bring the two together. By the time he entered Mayo Clinic's SPARK (Science Program for the Advancement of Research Knowledge) program as a high school junior in the summer of 2024, he also was no stranger&amp;hellip;</description><link>https://newsnetwork.mayoclinic.org/?p=418353</link><pubDate>Thursday, October 1, 2026</pubDate></item><item><title>Mayo Clinic researchers report early results from therapy designed for a single patient with rare genetic form of ALS </title><description>Mayo Clinic researchers report encouraging early results from an experimental therapy targeting the genetic cause of a rare form of amyotrophic lateral sclerosis, or ALS. </description><link>https://newsnetwork.mayoclinic.org/?p=417869</link><pubDate>Thursday, October 1, 2026</pubDate></item><item><title>Distinct gut microbiome patterns found in 5 cancer groups and in early-onset cancers</title><description>Ruben Mars, Ph.D., works within an anaerobic chamber in the Microbiomics Program laboratory at Mayo Clinic. Mayo Clinic findings also link specific gut bacteria to cancer survival and identify a pretreatment signal associated with chemotherapy toxicity ROCHESTER, Minn. — Mayo Clinic researchers have discovered distinct gut microbiome patterns in adults age 50 or younger with colorectal and breast cancers compared with those diagnosed later in life — one of several findings from an analysis of&amp;hellip;</description><link>https://newsnetwork.mayoclinic.org/?p=417910</link><pubDate>Tuesday, September 29, 2026</pubDate></item><item><title>Study finds fractionated radiosurgery reduces recurrence after surgery for brain metastases, may improve survival</title><description>ROCHESTER, Minn. — Mayo Clinic researchers led a multicenter study that found dividing radiation into several treatments, known as fractionated stereotactic radiosurgery, reduced the risk of cancer returning after surgery for brain metastases and was associated with improved survival compared with delivering radiation in a single treatment. The findings are being presented today at the 2026 American Society for Radiation Oncology (ASTRO) Annual Meeting in Boston. Brain metastases, also called metastatic brain tumors, are cancerous&amp;hellip;</description><link>https://newsnetwork.mayoclinic.org/?p=418244</link><pubDate>Monday, September 28, 2026</pubDate></item><item><title>Mayo Clinic experts present radiation oncology research at ASTRO 2026</title><description>Getty Images ROCHESTER, Minn. — Mayo Clinic researchers will present findings on emerging technologies, precision treatments and new radiation therapy techniques at the 2026 American Society for Radiation Oncology (ASTRO) Annual Meeting, Sept. 26–30 in Boston. Mayo Clinic experts will participate in nearly 65 poster, education, quick-pitch, scientific, oral, plenary and presidential sessions and present 45 abstracts. Their presentations will cover topics ranging from artificial intelligence (AI) and advanced technologies in radiation therapy to clinical&amp;hellip;</description><link>https://newsnetwork.mayoclinic.org/?p=418166</link><pubDate>Friday, September 25, 2026</pubDate></item><item><title>Multicancer blood test detects 17 cancer types in large prospective study</title><description>Getty Images ROCHESTER, Minn. — A large prospective study published today in Nature Medicine found that a blood test designed to detect multiple cancers identified cancer signals across 17 broad cancer types, such as ovarian, lung, breast and colorectal cancers, and many which do not have recommended screening tests. Mayo Clinic was among the institutions participating in the prospective, interventional study, which enrolled 35,878 adults age 50 and older. Karthik Giridhar, M.D., a Mayo Clinic&amp;hellip;</description><link>https://newsnetwork.mayoclinic.org/?p=418111</link><pubDate>Tuesday, September 22, 2026</pubDate></item><item><title>Study shows reprogramming thyroid tumors may improve CAR-T cell therapy</title><description>Saad Kenderian, M.B., Ch.B., uses a multi-channel pipette in the CAR-T Cell Engineering Laboratory. ROCHESTER, Minn. — Mayo Clinic researchers have identified a strategy that could help chimeric antigen receptor-T cell therapy, or CAR-T cell therapy, overcome a major barrier to treating solid tumors: Cancer cells can change in ways that allow them to hide from immune cells designed to attack them. In a preclinical study published in Molecular Cancer, researchers found that drugs used&amp;hellip;</description><link>https://newsnetwork.mayoclinic.org/?p=417896</link><pubDate>Friday, September 18, 2026</pubDate></item><item><title>Mayo Clinic first to study minibeam radiotherapy in patients with difficult-to-treat cancers</title><description>Radiation oncology medical physicist Dr. Michael Grams holds a device called a tungsten collimator that divides a conventional radiation beam into submillimeter-wide beamlets. ROCHESTER, Minn. — Mayo Clinic researchers report encouraging results using a new radiation technique called minibeam radiotherapy to treat patients with treatment-resistant cancers in or near the skin. The technique delivers very high doses of radiation through closely spaced, extremely narrow beams while limiting radiation exposure to healthy tissue between the beams. &amp;hellip;</description><link>https://newsnetwork.mayoclinic.org/?p=417827</link><pubDate>Wednesday, September 16, 2026</pubDate></item><item><title>Can disease be identified before symptoms begin? Mayo Clinic researchers are looking for answers</title><description>Mayo Clinic researchers are combining biological, environmental and health data with artificial intelligence to identify changes that may signal disease years before clinical symptoms appear  By the time doctors diagnose Alzheimer's disease, heart failure or cancer, the biological processes behind the illness may have been unfolding silently for years or even decades.&amp;nbsp; Mayo Clinic wants to make those invisible years a new target for medicine.&amp;nbsp; The healthcare organization is undertaking a sweeping research effort, called&amp;hellip;</description><link>https://newsnetwork.mayoclinic.org/?p=417775</link><pubDate>Monday, September 14, 2026</pubDate></item><item><title>AI-assisted approach helps novice users capture heart ultrasound images, identify aortic stenosis </title><description>ROCHESTER, Minn. — Mayo Clinic researchers tested an approach that uses artificial intelligence (AI) to help people without previous ultrasound experience capture heart images and identify patients who may have a common and serious heart valve condition. In a study published in JAMA Cardiology and presented at the 2026 ESC Congress, after four hours of training, novice users were able to collect focused heart ultrasound images while using  AI models to guide their image collection&amp;hellip;</description><link>https://newsnetwork.mayoclinic.org/?p=417632</link><pubDate>Wednesday, September 2, 2026</pubDate></item><item><title>5 subtypes of common liver disease discovered -- including rapidly progressing genetic forms</title><description>ROCHESTER, Minn. — A liver disease affecting nearly 30% of adults worldwide is not a single illness but five biologically distinct subtypes, Mayo Clinic researchers have found. Each carries different risks for heart disease, liver failure, cancer and the need for liver transplantation. The study, published in Nature Communications and conducted in collaboration with scientists at Virginia Tech, shows that metabolic dysfunction-associated steatotic liver disease has multiple pathways — some tied to obesity and diabetes,&amp;hellip;</description><link>https://newsnetwork.mayoclinic.org/?p=414811</link><pubDate>Wednesday, September 2, 2026</pubDate></item><item><title>Scientists uncover microbiome signaling system that could open new paths for IBS-related constipation</title><description>Helen Xiao, Ph.D., and Ruben Mars, Ph.D., work in the Mayo Clinic Microbiomics Program laboratory. ROCHESTER, Minn. — Mayo Clinic researchers have discovered that chemical signals produced by gut bacteria work together to control intestinal movement. One bacterial signal helps set the intestines in motion, while another primes gut cells to respond more strongly, amplifying the effect. The research expands scientists' understanding of how the gut microbiome communicates with the body, moving beyond the traditional&amp;hellip;</description><link>https://newsnetwork.mayoclinic.org/?p=417487</link><pubDate>Monday, August 31, 2026</pubDate></item><item><title>Mayo Clinic study estimates cancer risk in patients with pancreatic cysts, advancing early detection </title><description>ROCHESTER, Minn. — Mayo Clinic researchers have estimated the risk that pancreatic cysts with worrisome or high-risk features will progress to pancreatic cancer or advanced precancerous changes within three years. The findings, published in Gastroenterology, could help physicians and patients better assess risk and make more informed decisions about whether to monitor a cyst or consider surgery.&amp;nbsp; The prospective study found that risk increased with the number of worrisome features, or findings that the cyst&amp;hellip;</description><link>https://newsnetwork.mayoclinic.org/?p=417415</link><pubDate>Thursday, August 20, 2026</pubDate></item><item><title>Mayo Clinic AI model helps clinicians detect heart obstruction using routine ultrasound images</title><description>PHOENIX — Mayo Clinic researchers have developed and externally validated an artificial intelligence (AI) model that can identify a potentially significant heart obstruction from routine ultrasound videos without relying on specialized Doppler imaging. The technology could help clinicians flag patients with hypertrophic cardiomyopathy (HCM) who may need additional testing, particularly in settings where specialized echocardiography expertise is limited. Study findings are published in Circulation: Cardiovascular Imaging.   HCM is a genetic condition that causes the heart&amp;hellip;</description><link>https://newsnetwork.mayoclinic.org/?p=417409</link><pubDate>Wednesday, August 19, 2026</pubDate></item><item><title>International study identifies promising therapy to prevent relapses in rare neurological disease</title><description>ROCHESTER, Minn. — An international study led by Mayo Clinic researchers has identified interleukin-6 (IL-6) receptor blockers as a promising option for preventing relapses in myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD). MOGAD is a rare autoimmune neurological disorder that can cause vision loss, paralysis and other serious neurological complications. The study, published in JAMA Neurology, provides one of the largest real-world evaluations to date of IL-6 receptor blockade in patients with MOGAD and offers new&amp;hellip;</description><link>https://newsnetwork.mayoclinic.org/?p=417251</link><pubDate>Thursday, August 6, 2026</pubDate></item><item><title>How scientists hope to retrain the immune system after an organ transplant</title><description>Organ transplantation has transformed countless lives, offering hope to people with end-stage organ failure. But for many patients, the journey doesn't end with surgery. Lifelong anti-rejection medications protect transplanted organs, but they also can increase the risk of infection, cancer and other serious health complications. On the latest episode of "Tomorrow's Cure," host Lindsay Sievert explores a question researchers have pursued for decades: What if the immune system could be taught to accept a transplanted&amp;hellip;</description><link>https://newsnetwork.mayoclinic.org/?p=417212</link><pubDate>Wednesday, August 5, 2026</pubDate></item><item><title>First-in-class small molecule inhibitor designed with AI support shows promise against pancreatic cancer in preclinical studies</title><description>Getty JACKSONVILLE, Fla. — Mayo Clinic researchers have developed an experimental drug with the help of artificial intelligence (AI) to target the "undruggable" PDZ-domain of GIPC1 protein that helps different types of cancer, including pancreatic cancer, to grow and resist treatment. In laboratory studies, the drug slowed tumor growth, improved survival and enhanced the effects of the chemotherapy drug gemcitabine. The findings, published in Cell Reports, also demonstrate how AI could help develop a small&amp;hellip;</description><link>https://newsnetwork.mayoclinic.org/?p=417235</link><pubDate>Wednesday, August 5, 2026</pubDate></item><item><title>Researchers discover immune 'off switch' used by cancer cells </title><description>ROCHESTER, Minn. — Mayo Clinic researchers have identified a protein that cancer cells use to shut down the body's immune response, a discovery that could help scientists develop new treatments that make cancer immunotherapies more effective. Published in the Journal of Clinical Investigation, the study identifies a previously unknown role for a protein called TRAILshort, which acts like an immune "off switch." The researchers found that TRAILshort prevents T cells — the immune system's primary&amp;hellip;</description><link>https://newsnetwork.mayoclinic.org/?p=417184</link><pubDate>Monday, August 3, 2026</pubDate></item></channel></rss>