Publications

  1. Leslie JB, Trentman TL, Misra, Rosenfeld, Seamans, Caswell, Watkins, Hentz, Buckley. Is 10 mg/Kg Superior to 6.5 mg/Kg for Sedation in Patiens Undergoing Regional Anesthesia Blocks Prior to Orthopedic Surgery? Anesthesia Clinical Research. 2015.
  2. Long JB, Galdi L, Hentz JG, Leslie JB, Magtibay PM, Kho RMC, Cornella JL, Magrina JF. Prevention of postoperative nausea and vomiting in elective hysterectomy: a prospective, randomized, placebo controlled outcomes trial of aprepitant NK-1-receptor antagonist. Open Anesthesiol J. 2014; 4:301-7. Epub 2014 Dec
  3. Apfel CC, Philip BK, Cakmakkaya OS, Shilling A, Shi YY, Leslie JB, Allard M, Turan A, Windle P, Odom-Forren J, Hooper VD, Radke OC, Ruiz J, Kovac A. Who is at risk for postdischarge nausea and vomiting after ambulatory surgery? Anesthesiology. 2012 Sep; 117(3):475-86.
    View PubMed
  4. Pergolizzi JV, Philip BK, Leslie JB, Taylor R, Raffa RB. Perspectives on transdermal scopolamine for the treatment of postoperative nausea and vomiting. J Clin Anesth. 2012 Jun; 24(4):334-45.
    View PubMed
  5. Apfel C, Allard M, Hooper V, Kovac A, Leslie J, Miaskowski C, Odom-Forren J, Philip B, Ruiz J, Shilling A, Whelan R, Turan A. A Simplified Risk Score to Predict Severe Post-Surgical Pain in Ambulatory Patients. N Engl J Med (In press). 2012.
  6. Beard TL, Leslie JB, Nemeth J. The opioid component of delayed gastrointestinal recovery after bowel resection. J Gastrointest Surg. 2011 Jul; 15(7):1259-68. Epub 2011 Apr 15.
    View PubMed
  7. Pappagallo M, Leslie JB, Raffa RB, Kash P, Fleischer C, Sinclair N, Labhestwar S, Di Lorenzo L, Tabor A. Evaluation of a novel topical essential oxygen oil for the treatment of pain in acute tendinopathy and sprains. Muscles Ligaments Tendons J. 2011 Jan; 1(1):25-30. Epub 2011 Oct 30.
    View PubMed
  8. Leslie JB, Viscusi ER, Pergolizzi JV Jr, Panchal SJ. Anesthetic Routines: The Anesthesiologist's Role in GI Recovery and Postoperative Ileus. Adv Prev Med. 2011; 2011:976904 Epub 2010 Dec 29
    View PubMed
  9. Leslie JB, MacLaren R, Saclarides TJ. The evolving multimodal management plan for postoperative ileus. MedscapeCME. Available at: http://cme.medscape.com/viewarticle/707766.2009;
  10. Viscusi ER, Gan TJ, Leslie JB, Foss JF, Talon MD, Du W, Owens G. Peripherally acting mu-opioid receptor antagonists and postoperative ileus: mechanisms of action and clinical applicability. Anesth Analg. 2009 Jun; 108(6):1811-22.
    View PubMed
  11. Bell T, Annunziata K, Leslie JB. Opioid-induced constipation negatively impacts pain management, productivity, and health-related quality of life: findings from the National Health and Wellness Survey. J Opioid Manag. 2009 May-Jun; 5(3):137-44.
    View PubMed
  12. Leslie JB, Perolizzi JV, Macario A, Apfel CC, Clair D, Richmond C, Florio F, Auster M. Prospective evaluation of the efficacy of spinal decompression via the DRX9000 for chronic low back pain. The Journal of Medicine. 2008 Sep; 1.
  13. Apfel CC, Malhotra A, Leslie JB. The role of neurokinin-1 receptor antagonists for the management of postoperative nausea and vomiting. Curr Opin Anaesthesiol. 2008 Aug; 21(4):427-32.
    View PubMed
  14. Candiotti KA, Kovac AL, Metson TI, Clerici G, Gan TJ, Leslie JA. A randomized, double-blind study to evaluate the efficacy and safety of three different doses of palonosetron versus placebo for preventing postoperative nausea and vomiting. 2008 International Anesthesia Research Society. 2008 Aug; 107(2).
  15. Leslie JB. Alvimopan: a peripherally acting mu-opioid receptor antagonist. Drugs Today (Barc). 2007 Sep; 43: (9)611-25.
    View PubMed
  16. Leslie JB. Advances to block the adverse side effects of opioid analgesics on the gastrointestinal tract without blocking their beneficial analgesic effects. US Gastroenterology Review. 2007:94-7.
  17. Delaney C, Kehlet H, Senagore A, Bauer AJ, Beart R, Billingham R, Coleman RL, Dozois EJ, Leslie JB, Marks J, Megibow AJ, Michelassi F, Steinbrook RA. Postoperative ileus: profiles, risk factors, and definitions-a framework for optimizing surgical outcomes in patients undergoing major abdominal and colorectal surgery. Clinical Consensus Update in General Surgery. 2006 May 1; 1(2):1-28.
  18. Leslie JB, Gan TJ. Meta-analysis of the safety of 5-HT3 antagonists with dexamethasone or droperidol for prevention of PONV. Ann Pharmacother. 2006 May; 40(5):856-72. Epub 2006 May 02.
    View PubMed
  19. Leslie JB. Alvimopan for the management of postoperative ileus. Ann Pharmacother. 2005 Sep; 39(9):1502-10. Epub 2005 Aug 02.
    View PubMed
  20. Leslie JB. How can we best prevent or treat postoperative nausea and vomiting? Curr Opin Anaesthesiol. 2001 Dec; 14 (6):623-7
    View PubMed
  21. Slaughter TF, Faghih F, Greenberg CS, Leslie JB, Sladen RN. The effects of epsilon-aminocaproic acid on fibrinolysis and thrombin generation during cardiac surgery. Anesth Analg. 1997 Dec; 85(6):1221-6.
    View PubMed
  22. Berkowitz DE, Richardson C, Elliott DA, Leslie JB, Schwinm DA. Hypotension Resistant to Therapy with Alpha-Receptor Agonists Complicating Cardiopulmonary Bypass: Lithium as a Potential Cause. Anesth & Analg. 1996; 82:1082-5.
  23. Leslie JB, Bennett-Guerrero E, Jimenez JL, White WD, D’Amico ED, Baldwin BI, Schwim DA, Duke T3 Study Group. Cardiovascular Effects of Intravenous Triiodothyromine in Patients Undergoing Coronary Artery Bypass Graft Surgery. Journal American Medical Association. 1996; 275:687-92.
  24. Slaughter TF, LeBleu TH, Douglas JM, Leslie JB, Parker JK, Greenberg CS. Characterization of Prothrombin Activation during Cardiac Surgery by Hemostatic Molecular Markers. Anesthesiology. 1994; 80:520-6.
    View PubMed
  25. Leslie JB, Brister N, Levy JH, Yared JP, Marty A, Martin H, Hines R, Savino J, Cohen M. Treatment of Postoperative Hypertension Following Coronary Artery Bypass Surgery: Double Blind Comparison of Intravenous Isradipine and Sodium Nitroprusside. Circulation. 1994; 90 (part 2):II256-II61.
  26. Scuderi P, Wetchler B, Sung Y F, Mingus M, DuPen S, Claybon L, Leslie JB, Talke P, Apfelbaum J, Sharifi Azad S, Williams M. Treatment of Postoperative Nausea and Vomiting After Outpatient Surgery with the 5 HT3 Antagonists Ondansetron. Anesthesiology. 1993; 78:15-20.
    View PubMed
  27. Leslie JB. Incidence and Etiology of Perioperative Hypertension. Acta Anaesthesiol Scand. 1993; 37(suppl 99):5-9.
  28. Leslie JB. Hemodynamics and Tissue Specificity with Isradipine. Acta Anaesthesiol Scand 33 37. 1993; 37: (suppl 99)33-7.
  29. Ansel J, Klassen V, Lew R, Ball S, Weinstein M, VanderSalm TV, Okike N, Gratz I, Leslie JB, Roberts A, Fleming N, Salzman P. Does Desmopressin Acetate Prophylaxis Reduce Blood Loss After Valvular Heart Operations? A Randomized Double Blind Study. J Thorac Cardiovasc Surg. 1992; 104:117-23.
    View PubMed
  30. Du Pen S, Scuderi P, Wetchler B, Sung Y F, Mingus M, Clayborn L, Leslie JB, Talke P, Apfelbaum J, Sharifi Azad S, Williams M. Ondansetron in the Treatment of Postoperative Nausea and Vomiting in ambulatory outpatients: a dose comparative, stratified, multicentre study. Eur J Anaesthesiology. 1992; 9:55-62.
  31. Leslie JB, Hawks SJ, DeBree AS, Croughwell NH, Ginsberg B, Leone B, Ohman M, Reves JG. Patient Controlled Sedation during Cardiac Angioplasty, Anesthesia & Sedation by Continuous Infusion. Excerpta Medica. 1991:1-7.
  32. Leslie JB, Knopes KD. Pathophysiology of Hypertension and Tachycardia. J Cardiothoracic Anesth. 1990; 4:3 6.
  33. Sladen R, Klamerus K, Leslie JB, et al. Labetalol for the control of Elevated Blood Pressure Following Coronary Bypass Grafting. J Cardiothor Anesth. 1990; 4:210-221.
  34. Knopes KD, Leslie JB, London M. Pathophysiology and Treatment of Myocardial Ischemia. J Cardiothoracic Anesth. 1990; 4:51 54.
  35. Leslie JB, Kalayjian RW, McLoughlin TM, Plachetka JR. Attenuation of the Hemodynamic Responses to Endotracheal Intubation with Preinduction Intravenous Labetalol. J Clinical Anesth. 1989; 1:194 200.
  36. Flezzani P, McIntyre RW, Xuan YT, Su YF, Leslie JB, Watkins WD. Atrial natriuretic peptide plasma levels during cardiac surgery. J Cardiothorac Anesth. 1988 Jun; 2(3):274-80.
    View PubMed
  37. Greeley WG, Leslie JB, Reves JG, Watkins WD. Eicosanoids and the Cardiovascular System: A review and update. J Cardiothor Anesth. 1987; 4:331-349.
  38. Leslie JB, Kalayjian RJ, Sirgo MA, Plachetka J, Watkins WD. Intravenous Labetalol for the Treatment of Postoperative Hypertension. Anesthesiology. 1987; 67:413-416.
    View PubMed
  39. Russell RD, Leslie JB, Su YF, Watkins WD, Chang KJ. Continuous Intrathecal Opioid Analgesia: Tolerance and Cross Tolerance of Mu and Delta Spinal Opioid Receptors. J Pharm Exp Ther. 1987; 240(1):150 158.
  40. Russell RD, Leslie JB, Su YF, Watkins WD, Chang KJ. Continuous Intrathecal Opioid Analgesia: Tolerance and Cross Tolerance of Spinal Opioid Receptor Subtypes. NIDA Research Monograph, Advances in Endogenous and Exogenous Opioid Peptides. INRC Proceedings. 1986.
  41. Leslie JB, Watkins WD. Eicosanoids in the Central Nervous System: A Review. J Neurosurg. 1985; 63:659 668.
    View PubMed
  42. Bromage PB, Camporesi E, Leslie JB. Epidural Narcotics in Volunteers: Sensitivity to Pain and to Carbon Dioxide. Pain. 1980; 9:145 160.
    View PubMed
  43. Schneider AB, Wells SA, Gunnells JC, Leslie JB, Sherwood LM. Regulation of Function of Transplanted Parathyroid Glands in Man. Amer J Med. 1977; 63:710 718.
    View PubMed
  44. Leslie JB, Gunnells JC, Sherwood LM, Schneider AB, Wells SA. Physiologic Function of Transplanted Parathyroid Glands in Man. Surgical Forum 315317. 1976; XXVII: 1976.