Jacksonville, FL: FL 904-719-6136
Phoenix/Scottsdale, AZ: AZ 480-933-8382
Rochester, MN: MN 507-405-2864

Understand Menopause and Discover Relief From Symptoms

Find relief from hot flashes, sleep disturbances, mood changes, and other menopause symptoms at Mayo Clinic. Address your menopause concerns and learn your treatment options with the help of our women's health experts. We offer video, phone and in-person appointments to best meet your needs.

Menopause affects women in unique ways, and unlike women who are about to start their periods in adolescence, women often don't get "the talk" on what to expect when they are nearing the time when periods stop. Our menopause care experts listen to your questions and concerns and work with you to develop an individualized care plan that may include options such as lifestyle changes, hormone therapy, and hormone-free treatments. 

Find relief from menopause symptoms, such as:

•           Hot flashes

•           Night sweats

•           Mood changes

•           Sleep problems / insomnia

•           Weight gain / metabolism changes

•           Breast tenderness

•           Vaginal dryness

•           Pain with sex

•           Changes in sexual desire

Mayo Clinic Patient and Visitor Guidance During the COVID-19 Pandemic

Nothing is more important than your health and that of your family. To ensure your health is as protected as possible, Mayo Clinic is taking many new steps for patients and visitors coming to our campuses, clinics and hospitals during the COVID-19 pandemic. 

For many patients, access to direct care within Mayo Clinic's safe environment is in their best interest. We'll continue to offer phone and video visits as appropriate.


Jacksonville, FL: 904-719-6136
Phoenix/Scottsdale, AZ: 480-933-8382
Rochester, MN: 507-405-2864

So the mainstay of treatment for menopause, treating hot flashes and night sweats associated with menopause is hormones, typically an estrogen. And some women need a progestin based on if they have a uterus or not.

But for some women, they either choose not to use hormones or they can't use hormones because they have, for example, breast cancer or a blood clot. So in that case, we would choose a medication that's not a hormone, such as many of the non hormonal medications or other treatments that we have available. There are a lot of over-the-counter supplements that have been looked at to help symptoms of menopause. But when we do study them, we don't see that there are any more beneficial than placebo.

But there are some therapies that are not medication, such as cognitive behavioral therapy or even clinical hypnosis that has been studied and found to be effective at treating hot flashes and night sweats. So if women don't want to take hormones, they could consider one of the non hormonal medications. There's only one that's FDA approved for hot flashes and night sweats, it's called paroxetine, but it's in a class of medications called the SSRIs, also called antidepressants. But in this case we would be using it for treatment of menopausal symptoms and not necessarily for depression. There's also other medications like gabapentin, oxybutynin. All of those would be used off-label, but have data to support that they will treat the symptoms of menopause.

If women experience menopause, meaning they stopped menstruating for 12 months, younger than the age of 40, that's considered early menopause. And those women need to talk to their doctors about hormone replacement therapy. Because that's a different subset of women than those that are experiencing symptoms during the typical period of menopause. We find that women that go through early menopause that are on hormones have higher risks of things like heart disease, dementia. If they're not on hormone therapy until the average age of menopause, which is again 51 years of age.

So I want women to know that hormones are not bad. And if they don't have significant risk factors or other medical issues, that they could consider using hormones. And then I guess in that vein that if they can't use hormones or they choose not to, that we have other options to help treat them.

Why Choose Mayo Clinic?

  • More Experience

    Every year, more than 1 million people come to Mayo Clinic for care. Mayo Clinic's highly specialized experts are experienced in treating rare and complex conditions.

  • The Right Answers

    Getting effective treatment depends on identifying the right problem. In a recent study, 88 percent of patients who came to Mayo Clinic for a second opinion received a new or refined diagnosis.

  • Seamless Care

    At Mayo Clinic, every aspect of care is coordinated and teams of experts work together to provide exactly the care each patient needs. What might take months elsewhere is often done in days at Mayo Clinic

  • Unparalleled Expertise

    Mayo Clinic experts are some of the best in the world. Mayo Clinic consistently ranks among the top hospitals in the nation in the annual U.S. News & World Report rankings of best hospitals.