COVID-19: What you need to know
Featured conditions Brain tumor, breast cancer, colon cancer, congenital heart disease, heart arrhythmia. See more conditions.
Featured conditions
Mayo Clinic offers appointments in Arizona, Florida and Minnesota and at Mayo Clinic Health System locations.
Subscribe to Housecall
Our general interest e-newsletter keeps you up to date on a wide variety of health topics.
Margarine usually beats butter when it comes to heart health. Margarine is made from vegetable oils, so it contains no cholesterol, and it generally has more polyunsaturated and monounsaturated fat than butter does. But not all margarines are created equal, and some may even be worse than butter. In general, the more solid the margarine, the more trans fat it contains. Look for a spread with the lowest calories that tastes good to you, doesn't have trans fats and has the least amount of saturated fat.
Mayo Clinic does not endorse companies or products. Advertising revenue supports our not-for-profit mission.
Check out these best-sellers and special offers on books and newsletters from Mayo Clinic.