Brominated vegetable oil (BVO for short) is a food additive sometimes used to keep citrus flavoring from separating out in sodas and other beverages. Controversy has long surrounded the use of BVO. It's banned as a food additive in Europe but not in the U.S.
Health concerns about BVO stem from one of its ingredients, bromine. Bromine can irritate the skin and mucous membranes (the moist lining of the nose, mouth, lungs and stomach). Long-term exposure can cause neurologic symptoms such as headache, memory loss, and impaired balance or coordination. In the past these symptoms were seen with chronic use of bromide salts as sleep medications. Fortunately, these drugs are no longer widely available in the U.S.
However, there have been reports of people experiencing memory loss and skin and nerve problems after drinking excessive amounts (more than 2 liters a day) of soda containing BVO. While few people are likely to drink such large quantities, concern exists because bromine appears to build up in the body.
Although the Food and Drug Administration (FDA) originally categorized BVO as "generally recognized as safe," the agency later reversed that decision. The FDA continues to allow the use BVO in small amounts while it performs additional toxicology studies.
So what should you do? Check ingredient labels and don't drink large amounts of BVO-containing beverages. Better yet, take it one step further and cut back on all sugary drinks. Opt instead for healthier choices, such as water, low-fat milk and an occasional glass of 100% fruit juice.
May 10, 2019
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- Annual report: Research accomplishments and plans FY2016-FY2017. National Center for Toxicological Research. https://www.fda.gov/AboutFDA/CentersOffices/OC/OfficeofScientificandMedicalPrograms/NCTR/ResearchAccomplishmentsPlans/default.htm. Accessed May 6, 2019.
- Kim J-M, et al. Identifying method validation and measurement uncertainty of brominated vegetable oil in soft drinks and carbonated waters commonly consumed in South Korea. Food Chemistry. 2018;246:323.
- Chitranshi P, et al. Simple and rapid quantification of brominated vegetable oil in commercial soft drinks by LC-MS. Food Chemistry. 2016;213:567.
- Dietary Guidelines for Americans 2015-2020. U.S. Department of Health and Human Services. http://health.gov/dietaryguidelines/2015/guidelines/. Accessed April 20, 2019.
- Brominated vegetable oil. Title 21: Food and Drugs. Code of Federal Regulations. https://www.govinfo.gov/app/collection/CFR. Accessed May 2, 2019.
- Facts about bromine. Centers for Disease Control and Prevention. https://emergency.cdc.gov/agent/bromine/basics/facts.asp. Accessed May 6, 2019.
- Horowitz BZ. Bromism from excessive cola consumption. Journal of Toxicology: Clinical Toxicology. 1997;35:315.
- Jih DM, et al. Bromoderma after excessive ingestion of Ruby Red Squirt. New England Journal of Medicine. 2003;348:1932.
- Bendig P, et al. Mass spectra of methyl esters of brominated fatty acids and their presence in soft drinks and cocktail syrups. Rapid Communications in Mass Spectrometry. 2013;27:1083.
- Zeratsky KA (expert opinion). Mayo Clinic, Rochester, Minn. April 30, 2019.