Síndrome de las piernas inquietas

Por el personal de Mayo Clinic
24 de septiembre de 2026

Investigación

En Mayo Clinic, médicos capacitados en afecciones del sistema nervioso (neurólogos) y otros médicos estudian los factores genéticos y ambientales que pueden llevar al síndrome de las piernas inquietas. También buscan nuevos tratamientos para esta afección. Infórmese más en los sitios web de investigación en neurología y del Centro para la Medicina del Sueño.

Publicaciones

Consulte la lista de publicaciones de los médicos de Mayo Clinic sobre el síndrome de las piernas inquietas en PubMed, un servicio de la Biblioteca Nacional de Medicina.

  1. Restless legs syndrome. National Institute of Neurological Disorders and Stroke. https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Fact-Sheets/Restless-Legs-Syndrome-Fact-Sheet. Accessed Sept. 14, 2025.
  2. Ondo WG. Clinical features and diagnosis of restless legs syndrome and periodic limb movement disorder in adults. https://www.uptodate.com/contents/search. Accessed Sept. 14, 2025.
  3. Silber MH. Management of restless legs syndrome and periodic limb movement disorder in adults. https://www.uptodate.com/contents/search. Accessed Sept. 14, 2025.
  4. Winkelman JW, et al. Treatment of restless legs syndrome and periodic limb movement disorder: An American Academy of Sleep Medicine systematic review, meta-analysis, and GRADE assessment. Journal of Clinical Sleep Medicine. 2025; doi:10.5664/jcsm.11392.
  5. Gossard TR, et al. Restless legs syndrome: Contemporary diagnosis and treatment. Neurotherapeutics. 2021; doi:10.1007/s13311-021-01019-4.
  6. Allen RP, et al. Restless legs syndrome/Willis-Ekbom disease diagnostic criteria: Updated International Restless Legs Syndrome Study Group (IRLSSG) consensus criteria — history, rationale, description, and significance. Sleep Medicine. 2014; doi:10.1016/j.sleep.2014.03.025.
  7. Xu Y, et al. Unraveling restless legs syndrome: A comprehensive review of current research and future directions. International Journal of General Medicine. 2025; doi:10.2147/IJGM.S544680.
  8. Ferri FF. Restless legs syndrome. In: Ferri's Clinical Advisor 2026. Elsevier; 2026. https://www.clinicalkey.com. Accessed Sept. 14, 2025.
  9. Ami TR. Allscripts EPSi. Mayo Clinic. Nov. 14, 2023.
  10. Song P, et al. The global and regional prevalence of restless legs syndrome among adults: A systematic review and modelling analysis. Journal of Global Health. 2024; doi:10.7189/jogh.14.04113.
  11. Winkelman JW, et al. Treatment of restless legs syndrome and periodic limb movement disorder: An American Academy of Sleep Medicine clinical practice guideline. Journal of Clinical Sleep Medicine. 2025; doi:10.5664/jcsm.11390.
  12. Sleep center directory. American Academy of Sleep Medicine. https://sleepeducation.org/sleep-center. Accessed Sept. 22, 2025.
  13. Kellerman RD, et al. Sleep disorders. In: Conn's Current Therapy 2025. Elsevier; 2025. https://www.clinicalkey.com. Accessed Sept. 14, 2025.
  14. Silber MH, et al. The management of restless legs syndrome: An updated algorithm. Mayo Clinic Proceedings. 2021; doi:10.1016/j.mayocp.2020.12.026.