Esclerosis múltiple

Por el personal de Mayo Clinic
05 de septiembre de 2026

Investigación

Los investigadores de Mayo Clinic trabajan para mejorar el diagnóstico y el tratamiento de la esclerosis múltiple. Algunas de las iniciativas específicas son buscar las causas de la enfermedad y desarrollar estrategias para la remielinización y la regeneración de los axones.

Infórmese más sobre esta investigación en los laboratorios de Mayo Clinic y en el Centro para la Esclerosis Múltiple y la Neurología Autoinmunitaria.

Publicaciones

Consulte en PubMed una lista de publicaciones escritas por los médicos de Mayo Clinic sobre la esclerosis múltiple. PubMed es un servicio de la National Library of Medicine (Biblioteca Nacional de Medicina).

  1. What is multiple sclerosis? National Multiple Sclerosis Society. https://www.nationalmssociety.org/What-is-MS. Accessed June 10, 2024.
  2. Clinical overview: Multiple sclerosis. Elsevier Point of Care. 2023. https://www.clinicalkey.com. Accessed June 19, 2024.
  3. Olek MJ, et al. Clinical presentation, course, and prognosis of multiple sclerosis in adults. https://www.uptodate.com/contents/search. Accessed June 19, 2024.
  4. Olek MJ, et al. Pathogenesis and epidemiology of multiple sclerosis. https://www.uptodate.com/contents/search. Accessed June 19, 2024.
  5. Olek MJ, et al. Evaluation and diagnosis of multiple sclerosis in adults. https://www.uptodate.com/contents/search. Accessed June 19, 2024.
  6. Olek MJ, et al. Treatment of acute exacerbations of multiple sclerosis in adults. https://www.uptodate.com/contents/search. Accessed June 19, 2024.
  7. Olek MJ, et al. Initial disease-modifying therapy for relapsing-remitting multiple sclerosis in adults. https://www.uptodate.com/contents/search. Accessed June 19, 2024.
  8. Olek MJ, et al. Clinical use of monoclonal antibody disease-modifying therapies for multiple sclerosis. https://www.uptodate.com/contents/search. Accessed June 19, 2024.
  9. Olek MJ, et al. Clinical use of oral disease-modifying therapies for multiple sclerosis. https://www.uptodate.com/contents/search. Accessed June 19, 2024.
  10. Olek MJ, et al. Symptom management of multiple sclerosis in adults. https://www.uptodate.com/contents/search. Accessed June 19, 2024.
  11. Olek MJ, et al. Overview of disease-modifying therapies for multiple sclerosis. https://www.uptodate.com/contents/search. Accessed June 19, 2024.
  12. Olek MJ, et al. Manifestations of multiple sclerosis in adults. https://www.uptodate.com/contents/search. Accessed June 19, 2024.
  13. Jankovic J, et al., eds. Multiple sclerosis and other inflammatory demyelinating diseases of the central nervous system. In: Bradley and Daroff's Neurology in Clinical Practice. 8th ed. Elsevier; 2022. https://www.clinicalkey.com. Accessed June 19, 2024.
  14. Pizzorno JE, et al., eds. Multiple sclerosis. In: Textbook of Natural Medicine. 5th ed. Elsevier; 2021. https://www.clinicalkey.com. Accessed June 19, 2024.
  15. Krämer J, et al. Bruton tyrosine kinase inhibitors for multiple sclerosis. Nature Reviews Neurology. 2023; doi:10.1038/s41582-023-00800-7.
  16. Pediatric MS. National Multiple Sclerosis Society. https://www.nationalmssociety.org/for-professionals/for-healthcare-professionals/managing-and-treating-ms/pediatric-ms. Accessed June 19, 2024.
  17. Multiple sclerosis. National Institute of Neurological Disorders and Stroke. https://www.ninds.nih.gov/health-information/disorders/multiple-sclerosis#. Accessed June 24, 2024.
  18. Saadeh RS, et al. CSF kappa free light chains: Cutoff validation for diagnosing multiple sclerosis. Mayo Clinic Proceedings. 2022; doi:10.1016/j.mayocp.2021.09.014.
  19. Nimmagadda R. Allscripts EPSi. Mayo Clinic. May 13, 2024.
  20. Deb C. CD8+ T cells cause disability and axon loss in a mouse model of multiple sclerosis. PLOS One. 2010; doi:101371/journal.pone.0012478.
  21. Fadul CE, et al. Safety and immune effects of blocking CD40 ligand in multiple sclerosis. Neurology Journals. 2021; doi:10.1212/NXI.0000000000001096.
  22. Nakamura K, et al. Ibudilast reduces slowly enlarging lesions in progressive multiple sclerosis. Multiple Sclerosis Journal. 2024; doi:10.1177/13524585231224702.
  23. Katz Sand I, et al. Mediterranean diet is linked to less objective disability in multiple sclerosis. Multiple Sclerosis Journal. 2023; doi:10.1177/13524585221127414.
  24. Kantarci OH, et al. Novel immunomodulatory approaches for the management of multiple sclerosis. Clinical Pharmacology & Therapeutics. 2014; doi:10.1038/clpt.2013.196.
  25. Winn HR, ed. Neuropsychological testing. In: Youmans and Winn Neurological Surgery. 8th ed. Elsevier; 2023. https://www.clinicalkey.com. Accessed Oct. 21, 2024.
  26. Hancock LM, et al. Neuropsychological manifestations of multiple sclerosis. Neurologic Clinics. 2024; doi:10.1016/j.ncl.2024.05.010.