Síndrome de QT largo

Por el personal de Mayo Clinic
16 de septiembre de 2026

Investigación

Los investigadores de Mayo Clinic estudian de manera permanente nuevas formas de detectar, diagnosticar y tratar el síndrome de QT largo y otras causas de muerte súbita. El equipo de investigación de Mayo ha estudiado de forma exhaustiva la genética del síndrome de QT largo. Los temas de investigación más recientes han incluido el uso de la inteligencia artificial y el control por electrocardiograma remoto para el síndrome de QT largo.

Obtenga más información acerca de las investigaciones del QT largo que se llevan a cabo en el Windland Smith Rice Sudden Death Genomics Laboratory (Laboratorio de Genómica de Muerte Súbita de Windland Smith Rice) y en el Centro para la Investigación Cardiovascular de Mayo Clinic.

Publicaciones

Consulte en PubMed una lista de publicaciones sobre el síndrome de QT largo escritas por los médicos de Mayo Clinic. PubMed es un servicio de la National Library of Medicine (Biblioteca Nacional de Medicina).

  1. What is long QT syndrome? National Heart, Lung, and Blood Institute. https://www.nhlbi.nih.gov/health/long-qt-syndrome. Accessed March 13, 2024.
  2. Conduction disorders. American Heart Association. https://www.heart.org/en/health-topics/arrhythmia/about-arrhythmia/conduction-disorders. Accessed March 13, 2024.
  3. Schwartz PJ, et al. Congenital long QT syndrome: Epidemiology and clinical manifestations. https://www.uptodate.com/contents/search. Accessed March 13, 2024.
  4. Giudicessi JR, et al. Prevalence and clinical phenotype of concomitant long QT syndrome and arrhythmogenic bileaflet mitral valve prolapse. International Journal of Cardiology. 2019; doi:10.1016/j.ijcard.2018.09.046.
  5. Berul CI. Acquired long QT syndrome: Definitions, pathophysiology, and causes. https://www.uptodate.com/contents/search. Accessed March 13, 2024.
  6. Waddell-Smith KE, et al. Pre-test probability and genes and variants of uncertain significance in familial long QT syndrome. Heart, Lung and Circulation. 2020; doi:10.1016/j.hlc.2019.
  7. AskMayoExpert. Significance of a long QT interval (adult). Mayo Clinic; 2020.
  8. How the heart works. National Heart, Lung, and Blood Institute. https://www.nhlbi.nih.gov/health/heart. Accessed March 13, 2024.
  9. AskMayoExpert. Prolonged QT interval: Signs and symptoms (adult). Mayo Clinic; 2020.
  10. Arrhythmia. National Heart, Lung, and Blood Institute. https://www.nhlbi.nih.gov/health/arrhythmias. Accessed March 13, 2024.
  11. Schwartz PJ, et al. Congenital long QT syndrome: Diagnosis. https://www.uptodate.com/contents/search. Accessed March 13, 2024.
  12. Ferri FF. Long QT syndrome. In: Ferri's Clinical Advisor 2022. Elsevier; 2022. https://www.clinicalkey.com. Accessed March 13, 2024.
  13. Schwartz PJ, et al. Congenital long QT syndrome: Treatment. https://www.uptodate.com/contents/search. Accessed March 13, 2024.
  14. Bos JM, et al. Use of artificial intelligence and deep neural networks in evaluation of patients with electrocardiographically concealed long QT syndrome from the surface 12-lead electrocardiogram. JAMA Cardiology. 2021; doi:10.1001/jamacardio.2020.7422.
  15. Amedro P, et al. Health-related quality of life and physical activity in children with inherited cardiac arrhythmia or inherited cardiomyopathy: The prospective multicentre controlled QUALIMYORYTHM study rationale, design and methods. Health and Quality of Life Outcomes. 2021; doi:10.1186/s12955-021-01825-6.
  16. Ami TR. Allscripts EPSi. Mayo Clinic. March 29, 2024.
  17. Giudicessi JR, et al. Artificial intelligence-enabled assessment of the heart rate corrected QT interval using a mobile electrocardiogram device. Circulation. 2021; doi:10.1161/CIRCULATIONAHA.120.050231.
  18. Mayo Clinic Laboratories. Test ID: LQTSG. https://www.mayocliniclabs.com/test-catalog/overview/617351. Accessed March 15, 2024.
  19. Bos JM, et al. Mexiletine shortens the QT interval in patients with potassium channel-mediated type 2 long QT syndrome. Circulation. 2019; doi:10.1161/CIRCEP.
  20. Cuneo BF, et al. Mothers with long QT syndrome are at increased risk for fetal death: Findings from a multicenter international study. American Journal of Obstetrics and Gynecology. 2020; doi:10.1016/j.ajog.2019.09.004.
  21. Tobert KE, et al. Return-to-play for athletes with long QT syndrome or genetic heart diseases predisposing to sudden death. Journal of the American College of Cardiology. 2021; doi:10.1016/j.jacc.2021.04.026.
  22. Schwartz PJ, et al. Inherited cardiac arrhythmias. Nature Reviews: Disease Primer. 2020; doi:10.1038/s41572-020-0188-7.
  23. Al-Khatib SM, et al. 2017 AHA/ACC/HRS guideline for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society. Circulation. 2018; doi:10.1161/CIR.0000000000000549.
  24. Medical review (expert opinion). Mayo Clinic. May 1, 2020.
  25. Electrocardiogram. Mayo Clinic. https://www.mayoclinic.org/tests-procedures/ekg/about/pac-20384983. Accessed March 13, 2024.
  26. Medical review (expert opinion). Mayo Clinic. May 1, 2020.
  27. Long B, et al. Electrocardiographic manifestations of COVID-19. American Journal of Emergency Medicine. 2021; doi:10.1016/j.ajem.2020.12.060.
  28. AskMayoExpert. Evaluation of significant QT prolongation and/or serial QT lengthening (adult). Mayo Clinic; 2020.