Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Incidence not known

  1. Agitation
  2. bleeding gums
  3. bloating
  4. blood in the urine or stools
  5. bloody, black, or tarry stools
  6. blue lips, fingernails, or skin
  7. blurred vision
  8. burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  9. change in consciousness or confusion
  10. chest pain or discomfort
  11. chills
  12. clay-colored stools
  13. confusion
  14. constipation
  15. cough
  16. coughing or vomiting blood
  17. dark urine
  18. darkening of the skin
  19. decrease in urine volume or frequency
  20. decreased appetite
  21. depression
  22. difficult, fast, noisy breathing
  23. difficulty in passing urine (dribbling)
  24. difficulty swallowing
  25. dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  26. drowsiness
  27. dry mouth
  28. fainting
  29. fast, slow, irregular, pounding, or racing heartbeat or pulse
  30. feeling of hostility or irritability
  31. feeling of warmth
  32. feeling that something terrible will happen
  33. fever
  34. headache, sudden, severe
  35. heartburn
  36. hives, itching, or skin rash
  37. increased menstrual flow or vaginal bleeding
  38. increased sweating
  39. indigestion
  40. irregular, fast, slow, or shallow breathing
  41. large, flat, blue or purplish patches on the skin
  42. large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
  43. loss of consciousness
  44. muscle cramping, weakness, or tremors
  45. muscle pain or stiffness
  46. nausea
  47. nosebleeds
  48. numbness or tingling in the hands, feet, or lips
  49. overactive reflexes
  50. painful or difficult urination
  51. pains in the stomach, side, or abdomen, possibly radiating to the back
  52. pale skin
  53. pinpoint red or purple spots on the skin
  54. poor coordination
  55. prolonged bleeding from cuts
  56. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  57. red or black, tarry stools or dark urine
  58. restlessness
  59. seizures
  60. shivering
  61. sleepiness
  62. sunken eyes
  63. sweating
  64. swelling of the face, ankles, hands, feet, or lower legs
  65. stomach pain, cramping, or tenderness
  66. talking or acting with excitement you cannot control
  67. thirst
  68. tightness in the chest
  69. trembling or shaking
  70. twitching
  71. unusual bleeding or bruising
  72. unusual tiredness or weakness
  73. vomiting
  74. vomiting of material that looks like coffee grounds, severe and continuing
  75. weak or feeble pulse
  76. weakness or heaviness of the legs
  77. weight gain
  78. wrinkled skin
  79. yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

  1. Continuing ringing or buzzing or other unexplained noise in the ears
  2. decreased awareness or responsiveness
  3. diarrhea
  4. drowsiness
  5. enlarged pupils
  6. extremely high fever or body temperature
  7. fast, weak heartbeat
  8. hearing loss
  9. increase in heart rate
  10. restlessness
  11. severe sleepiness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Relaxed and calm feeling
  2. sleepiness

Incidence not known

  1. Belching
  2. bloated, full feeling
  3. blurred or loss of vision
  4. change in color perception
  5. cold sweats
  6. constricted, pinpoint, or small pupils (black part of the eye)
  7. cool, pale skin
  8. double vision
  9. excess air or gas in the stomach
  10. false or unusual sense of well-being
  11. flushed, dry skin
  12. fruit-like breath odor
  13. halos around lights
  14. increased hunger or thirst
  15. increased urination
  16. lack or loss of strength
  17. night blindness
  18. nightmares
  19. overbright appearance of lights
  20. red eyes
  21. redness of the skin
  22. seeing, hearing, or feeling things that are not there
  23. shakiness
  24. slurred speech
  25. trouble sleeping
  26. tunnel vision
  27. unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
  28. weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Portions of this document last updated: Aug. 01, 2019

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