Cangrelor (Intravenous Route) Description and Brand Names

Description and Brand Names

Drug information provided by: Merative, Micromedex®

US Brand Name

Kengreal

Descriptions

Cangrelor injection is used in patients undergoing percutaneous coronary intervention (PCI) to lower the risk of blood clots and heart attack.

A heart attack or stroke may occur when a blood vessel in the heart or brain is blocked by a blood clot. Cangrelor reduces the chance that a harmful blood clot will form by preventing certain cells in the blood from clumping together. This effect of cangrelor may also increase the chance of serious bleeding in some people.

This medicine is to be given only by or under the supervision of your doctor.

This product is available in the following dosage forms:

Powder for Solution

Before Using

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of cangrelor injection in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of cangrelor injection in the elderly.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Abrocitinib

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Aceclofenac
Acemetacin
Amtolmetin Guacil
Apixaban
Argatroban
Betrixaban
Bivalirudin
Bromfenac
Bufexamac
Caplacizumab-yhdp
Celecoxib
Choline Salicylate
Citalopram
Clonixin
Clopidogrel
Dabigatran Etexilate
Danaparoid
Desirudin
Desvenlafaxine
Dexibuprofen
Dexketoprofen
Diclofenac
Diflunisal
Dipyrone
Droxicam
Duloxetine
Edoxaban
Escitalopram
Etodolac
Etofenamate
Etoricoxib
Felbinac
Fenoprofen
Fepradinol
Feprazone
Floctafenine
Flufenamic Acid
Fluoxetine
Flurbiprofen
Fluvoxamine
Fondaparinux
Heparin
Ibuprofen
Indomethacin
Ketoprofen
Ketorolac
Lepirudin
Levomilnacipran
Lornoxicam
Loxoprofen
Lumiracoxib
Meclofenamate
Mefenamic Acid
Meloxicam
Milnacipran
Morniflumate
Nabumetone
Naproxen
Nepafenac
Niflumic Acid
Nimesulide
Nimesulide Beta Cyclodextrin
Oxaprozin
Oxyphenbutazone
Parecoxib
Paroxetine
Phenindione
Phenprocoumon
Phenylbutazone
Piketoprofen
Piroxicam
Prasugrel
Proglumetacin
Propyphenazone
Proquazone
Protein C
Rivaroxaban
Rofecoxib
Salicylic Acid
Salsalate
Sertraline
Sodium Salicylate
Sulindac
Tenoxicam
Tiaprofenic Acid
Tolfenamic Acid
Tolmetin
Valdecoxib
Venlafaxine
Vilazodone
Vortioxetine
Warfarin

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper Use

A nurse or other trained health professional will give you this medicine in a hospital. This medicine is given through a needle placed in one of your veins. It is given before the start of PCI.

Precautions

It is very important that your doctor check you closely while you are receiving this medicine. This will allow your doctor to see if the medicine is working properly and to check for unwanted effects. Blood tests may be needed to check for unwanted effects.

This medicine may increase your chance of bleeding and bruising. Check with your doctor right away if you notice any unusual bleeding or bruising, black, tarry stools, blood in the urine or stools, or pinpoint red spots on your skin.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

Abdominal or stomach pain or swelling
back pain
black, tarry stools
blood in the eyes
blood in the urine
bruising or purple areas on the skin
coughing up blood
decreased alertness
dizziness
headache
joint pain or swelling
nosebleeds

Less common

Difficult or labored breathing
tightness in the chest

Rare

Cough
difficulty with swallowing
fast heartbeat
hives, itching, or rash
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
noisy breathing
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
unusual tiredness or weakness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Portions of this document last updated: Feb. 01, 2024

Original article: https://www.mayoclinic.org/es-es/drugs-supplements/cangrelor-intravenous-route/description/drg-20146785

Cangrelor (Intravenous Route)