Urología

A continuación se enumeran ensayos clínicos actuales.

Filtrar esta lista de estudios según la ubicación, el estado del estudio y más.

1. Use of Tamsulosin to Reduce the Incidence and Duration of Postoperative Urinary Retention Following Spine Surgery

   Rochester, Minn.

   Postoperative urinary retention is a frequent complication of spinal surgeries and impacts a large portion of this population which results in increased morbidity as a result of increased number of catheterizations, urinary tract infections (UTIs) and prolonged hospital stays. With the addition of Tamsulosin, the investigators would anticipate a reduction in the incidence and duration of postoperative urinary retention and therefore a reduction in morbidity related to treatment of urinary retention as well as shortened hospital stays.

2. A Study to Evaluate 177Lu-PSMA-R2 in Patients with PSMA Positive Progressive, Metastatic, Castration Resistant Prostate Cancer

   Rochester, Minn.

   The purpose of this study is to determine the safety, tolerability and pharmacokinetics (how the study drug and imaging agent is absorbed, moves, and is eliminated by your body can be analyzed) and dosimetry (how much radiation taken by the organs and tumors can be measured) of the study drug 177Lu-PSMA-R2 and imaging agent 68Ga-PSMA-R2 in subjects who have progressive metastatic castration-resistant prostate cancer

3. A Study to Evaluate Support Services for Managing Urological Conditions

   Scottsdale/Phoenix, Ariz.

   The purpose of this study is to assess if men and women seeking care for urological diseases have interest in support services in conjunction with standard of care.

4. A Study to Evaluate Contouring Organs at Risk for Treatment Planning

   Scottsdale/Phoenix, Ariz., Jacksonville, Fla., Rochester, Minn.

   The purpose of this study is to determine:  if the artificial intelligence (AI)-generated results are less arduous than manual tracing by radiation oncologist, and the non-inferiority of the quality of AI vs. manual tracing.  These aims will be evaluated in a clinical environment to investigate the impact of an AI algorithm on the clinical workflow. 

   Radiotherapy treatment planning requires precise calculations of radiation exposure, not only for the target volumes (tissue containing malignancy), but of nearby organs-at-risk (OARs), in which the exposure needs to be minimized. Manual segmentation of these organs is a time-consuming task with high interobserver variability. Producing these segmentations automatically will reduce the time required for treatment planning and improve the interobserver variability.

5. Study of Validated Biomarkers in Urine for Patients with Adenocarcinoma of the Prostate

   Rochester, Minn.

   The purpose of this study is to assess the accuracy of DNA marker candidates (individually and in combination) assayed from urine and prostatic fluid (collected following digital prostate massage) for detection of prostate cancer.

6. A Study of Proton Radiation Divided into Fewer Doses for Low Risk Prostate Cancer

   Scottsdale/Phoenix, Ariz., Rochester, Minn.

   The purpose of this study is to compare the effects (good and bad) on patients with prostate cancer by comparing the standard dose of radiation therapy (44 treatments over 8½-9 weeks) with a higher daily dose of radiation (5 treatments over 1-2 weeks) to see if the effects of the treatments are similar or better.

7. A Study of Apalutamide in Participants With High‑Risk, Localized or Locally Advanced Prostate Cancer Who Are Candidates for Radical Prostatectomy

   Jacksonville, Fla.

   The purpose of this study is to determine if treatment with androgen deprivation therapy (ADT) plus apalutamide before and after radical prostatectomy in participants with high-risk localized or locally advanced prostate cancer results in an improvement in pathological complete response (pCR) rate and metastasis-free survival (MFS), as compared to ADT plus placebo.

8. A Study to Evaluate the Feasibility of Daily, Long-Term, Intermittent Fasting for Men on PSA Surveillance Following Radical Prostatectomy

   Rochester, Minn.

   The purpose of this study is to determine whether men treated for localized prostate cancer adhere to a long-term (months-years) daily intermittent fasting regimen, and to measure the levels of metabolic and prostate-cancer derived microparticles in the serum of men that practice a daily intermittent fasting regimen after treatment for localized, high-risk prostate cancer.

9. A Study of Advanced Magnetic Resonance Imaging of the Prostate/Pelvis using Associated Image Processing with or without MRI/Ultrasound Fusion Biopsy Guidance

   Rochester, Minn.

   The purpose of this study is to assess the advantages of new image processing software to workflow and productivity. This software has been shown in the literature to improve cancer detection.

10. MR-Guided Cryoablation of Prostate Bed Recurrences

    Rochester, Minn.

    The purpose of this research is to see if MR-guided cryoablation can effectively treat prostate tumor recurrences.