Chandan Krishna, M.D.

  1. Neurosurgeon
  1. Stonnington H, Shahbandi A, Bcharah G, Singh R, George DD, Furst T, Krishna C, Bydon M. Timing and Morbidity of Intracranial Meningioma Resection Complications. World Neurosurg. 2024 Mar; 183:e293-e303 Epub 2023 Dec 21
    View PubMed
  2. Wang L, Wang H, D'Angelo F, Curtin L, Sereduk CP, Leon G, Singleton KW, Urcuyo J, Hawkins-Daarud A, Jackson PR, Krishna C, Zimmerman RS, Patra DP, Bendok BR, Smith KA, Nakaji P, Donev K, Baxter LC, Mrugala MM, Ceccarelli M, Iavarone A, Swanson KR, Tran NL, Hu LS, Li J. Quantifying intra-tumoral genetic heterogeneity of glioblastoma toward precision medicine using MRI and a data-inclusive machine learning algorithm. PLoS One. 2024; 19 (4):e0299267 Epub 2024 Apr 03
    View PubMed
  3. Abi-Aad KR, Rahme RJ, Syal A, De La Pena NM, Turcotte EL, Patra DP, Jones B, Chong B, Krishna C, Bendok BR. Predictive Model Evaluating Risk of Hemorrhage in Intracranial Aneurysms: Analysis from Prospectively Collected HEAT Trial Database. World Neurosurg. 2023 Oct; 178:e315-e322 Epub 2023 July 20
    View PubMed
  4. Hu LS, D'Angelo F, Weiskittel TM, Caruso FP, Fortin Ensign SP, Blomquist MR, Flick MJ, Wang L, Sereduk CP, Meng-Lin K, De Leon G, Nespodzany A, Urcuyo JC, Gonzales AC, Curtin L, Lewis EM, Singleton KW, Dondlinger T, Anil A, Semmineh NB, Noviello T, Patel RA, Wang P, Wang J, Eschbacher JM, Hawkins-Daarud A, Jackson PR, Grunfeld IS, Elrod C, Mazza GL, McGee SC, Paulson L, Clark-Swanson K, Lassiter-Morris Y, Smith KA, Nakaji P, Bendok BR, Zimmerman RS, Krishna C, Patra DP, Patel NP, Lyons M, Neal M, Donev K, Mrugala MM, Porter AB, Beeman SC, Jensen TR, Schmainda KM, Zhou Y, Baxter LC, Plaisier CL, Li J, Li H, Lasorella A, Quarles CC, Swanson KR, Ceccarelli M, Iavarone A, Tran NL. Integrated molecular and multiparametric MRI mapping of high-grade glioma identifies regional biologic signatures. Nat Commun. 2023 Sep 28; 14 (1):6066 Epub 2023 Sept 28
    View PubMed
  5. Stonnington HO, Olson VA, Kalani MA, Krishna C, Patel NP, Bendok BR. Commentary: En Bloc Resection of a Cauda Equina Paraganglioma and Associated Intradural Hematoma After Diagnosis of Renal Clear Cell Carcinoma: 2-Dimensional Operative Video. Oper Neurosurg (Hagerstown) 2023 Feb 1; 24 (2):e144-e145 Epub 2022 Dec 09
    View PubMed
  6. Urcuyo JC, Curtin L, Langworthy JM, De Leon G, Anderies B, Singleton KW, Hawkins-Daarud A, Jackson PR, Bond KM, Ranjbar S, Lassiter-Morris Y, Clark-Swanson KR, Paulson LE, Sereduk C, Mrugala MM, Porter AB, Baxter L, Salomao M, Donev K, Hudson M, Meyer J, Zeeshan Q, Sattur M, Patra DP, Jones BA, Rahme RJ, Neal MT, Patel N, Kouloumberis P, Turkmani AH, Lyons M, Krishna C, Zimmerman RS, Bendok BR, Tran NL, Hu LS, Swanson KR. Image-localized biopsy mapping of brain tumor heterogeneity: A single-center study protocol. PLoS One. 2023; 18 (12):e0287767 Epub 2023 Dec 20
    View PubMed
  7. Patra DP, Syal A, Rahme RJ, Abi-Aad KR, Singh R, Turcotte EL, Jones BA, Meyer J, Hudson M, Chong BW, Dabus G, James RF, Krishna C, Bendok BR. A comparison of treating physician versus independent core lab assessments of post-aneurysm treatment imaging outcomes: an analysis of prospectively collected data from a randomized trial. J Neurosurg. 2022 Dec 9; 1-9 Epub 2022 Dec 09
    View PubMed
  8. Patra DP, Turcotte EL, Turkmani AH, Krishna C, Bendok BR. Microsurgical Resection of Optic Chiasm Cavernous Malformations: 2-Dimensional Operative Video. Oper Neurosurg (Hagerstown). 2022 Aug 1; 23 (2):e129 Epub 2022 May 11
    View PubMed
  9. Rangel I, Palmisciano P, Vanderhye VK, El Ahmadieh TY, Wahood W, Demaerschalk BM, Sands KA, O'Carroll CB, Krishna C, Zimmerman RS, Chong BW, Bendok BR, Turkmani AH. Optimizing Door-to-Groin Puncture Time: The Mayo Clinic Experience. Mayo Clin Proc Innov Qual Outcomes. 2022 Aug; 6 (4):327-336 Epub 2022 June 27
    View PubMed
  10. Abi-Aad KR, Rahme RJ, Patra DP, Turcotte EL, Richter KR, Merrill SA, Syal A, Neville MR, Hudson M, Garcia JO, Tawk RG, Chong BW, Krishna C, Bendok BR. Clinical outcomes of first- and second-generation hydrogel coils compared with bare platinum coils: a systematic literature review. Neurosurg Rev. 2022 Jun; 45 (3):1873-1882 Epub 2022 Jan 15
    View PubMed
  11. Patra DP, Demaerschalk BM, Chong BW, Krishna C, Bendok BR. A Renaissance in Modern and Future Endovascular Stroke Care. Neurosurg Clin N Am. 2022 Apr; 33 (2):169-183 Epub 2022 Mar 02
    View PubMed
  12. Patra DP, Welz ME, Turcotte EL, Pandey R, Vij K, Daly M, Rabon M, Korszen S, Zhou Y, Halpin B, Marchese ML, Syal A, Krishna C, Bendok BR. Real-Time MRI-Guided Stereotactic Aspiration of Spontaneous Intracerebral Hematoma: A Preclinical Feasibility Study. Oper Neurosurg (Hagerstown). 2022 Feb 1; 22 (2):80-86
    View PubMed
  13. Krishna C, DiNatale RG, Kuo F, Srivastava RM, Vuong L, Chowell D, Gupta S, Vanderbilt C, Purohit TA, Liu M, Kansler E, Nixon BG, Chen YB, Makarov V, Blum KA, Attalla K, Weng S, Salmans ML, Golkaram M, Liu L, Zhang S, Vijayaraghavan R, Pawlowski T, Reuter V, Carlo MI, Voss MH, Coleman J, Russo P, Motzer RJ, Li MO, Leslie CS, Chan TA, Hakimi AA. Single-cell sequencing links multiregional immune landscapes and tissue-resident T cells in ccRCC to tumor topology and therapy efficacy. Cancer Cell. 2021 May 10; 39 (5):662-677.e6 Epub 2021 Apr 15
    View PubMed
  14. Bydon M, Chen SG, Neal MD, Krishna C, Biedermann AJ, Paul TC, Yolcu YU, Goyal A, Bendok BR, Quinones-Hinojosa A, Spinner RJ, Meyer FB. Initiation of a Robotic Program in Spinal Surgery: Experience at a Three-Site Medical Center. Mayo Clin Proc. 2021 May; 96(5):1193-1202. Epub 2020 Dec 28.
    View PubMed
  15. Hu LS, Wang L, Hawkins-Daarud A, Eschbacher JM, Singleton KW, Jackson PR, Clark-Swanson K, Sereduk CP, Peng S, Wang P, Wang J, Baxter LC, Smith KA, Mazza GL, Stokes AM, Bendok BR, Zimmerman RS, Krishna C, Porter AB, Mrugala MM, Hoxworth JM, Wu T, Tran NL, Swanson KR, Li J. Uncertainty quantification in the radiogenomics modeling of EGFR amplification in glioblastoma. Sci Rep. 2021 Feb 16; 11 (1):3932
    View PubMed
  16. Abi-Aad KR, Rahme RJ, Syal A, Patra DP, Hudson M, Richter KR, Ward JD, Knis J, Nak Y, Turcotte E, Welz ME, Winter J, Krishna C, Chong B, Bendok BR. Quality of Life of Patients with Unruptured Intracranial Aneurysms Before and After Endovascular Coiling: A HEAT Trial Secondary Study and Systematic Review of the Literature. World Neurosurg. 2021 Feb; 146:e492-e500 Epub 2020 Oct 27
    View PubMed
  17. Mauler DJ, R Richter K, Merrill S, Valencia-Sanchez C, Krishna C, M Mrugala M. Troubleshooting an unusual complication following intrathecal chemotherapy delivered via Ommaya catheter: A case report. Mol Clin Oncol. 2020 Jul; 13 (1):76-79 Epub 2020 Apr 22
    View PubMed
  18. Curley KL, Krishna C, Maiti TK, McClendon J Jr, Bendok BR. Metal Hypersensitivity After Spinal Instrumentation: When to Suspect and How to Treat. World Neurosurg. 2020 Jul; 139:471-477 Epub 2020 Apr 24
    View PubMed
  19. Abi-Aad KR, Turcotte E, Patra DP, Welz ME, Maiti T, Hess R, Kalen B, Krishna C, Zimmerman RS, Bendok BR. Vascular Transposition of the Superior Cerebellar Artery Using a Fenestrated Clip and Fibrin Glue in Trigeminal Neuralgia: 2-Dimensional Operative Video. Oper Neurosurg (Hagerstown). 2020 Jul 1; 19 (1):E50-E51
    View PubMed
  20. Hoxworth JM, Eschbacher JM, Gonzales AC, Singleton KW, Leon GD, Smith KA, Stokes AM, Zhou Y, Mazza GL, Porter AB, Mrugala MM, Zimmerman RS, Bendok BR, Patra DP, Krishna C, Boxerman JL, Baxter LC, Swanson KR, Quarles CC, Schmainda KM, Hu LS. Performance of Standardized Relative CBV for Quantifying Regional Histologic Tumor Burden in Recurrent High-Grade Glioma: Comparison against Normalized Relative CBV Using Image-Localized Stereotactic Biopsies. AJNR Am J Neuroradiol. 2020 Mar; 41 (3):408-415 Epub 2020 Mar 12
    View PubMed
  21. Sattur MG, Abi-Aad KR, Welz ME, Aoun RJ, Krishna C, Purnell C, Alghoul M, Bendok BR. Extended Lateral Orbital Craniotomy: Anatomic Study and Initial Clinical Series of a Novel Minimally Invasive Pterional Approach. J Neurol Surg B Skull Base. 2020 Feb; 81 (1):88-96 Epub 2019 Feb 21
    View PubMed
  22. Turcotte EL, Abi-Aad KR, Hess RA, Welz ME, Patra DP, Krishna C, Bendok BR. Restoring Speech Using Neuroprosthetic Technology: A New Frontier for Patients with Aphasia. World Neurosurg 2019 Dec; 132:437-438 Epub 2019 Nov 19
    View PubMed
  23. Bendok BR, Abi-Aad KR, Rahme RJ, Turcotte EL, Welz ME, Patra DP, Hess R, Kalen B, Krishna C, Batjer HH. Tulip Giant Aneurysm Amputation and "Shingle Clip Cut Clip" Technique for Microsurgical Reconstruction of a Giant Thrombosed Middle Cerebral Artery Aneurysm. World Neurosurg. 2019 Nov; 131:166 Epub 2019 Aug 02
    View PubMed
  24. Chong BW, Bendok BR, Krishna C, Sattur M, Brown BL, Tawk RG, Miller DA, Rangel-Castilla L, Babiker H, Frakes DH, Theiler A, Cloft H, Kallmes D, Lanzino G. A Multicenter Pilot Study on the Clinical Utility of Computational Modeling for Flow-Diverter Treatment Planning. AJNR Am J Neuroradiol. 2019 Oct; 40 (10):1759-1765 Epub 2019 Sept 26
    View PubMed
  25. Munich SA, Krishna C, Cress MC, Dhillon GS, Pollina J, Levy EI. Diagnosis and endovascular embolization of a sacral spinal arteriovenous fistula with "holo-spinal" venous drainage World Neurosurgery. 2019 Aug; 128:328-32
  26. Patra DP, Krishna C, Turkmani A, Abi-Aad KR, Welz ME, Bendok BR. Letter: Management of a Previously Coiled Anterior Cerebral Artery Aneurysm in a Child: 3-Dimensional Operative Video. Oper Neurosurg (Hagerstown) 2019 Aug 1; 17 (2):E93-E94
    View PubMed
  27. Tian F, Abi-Aad KR, Bendok BR, Krishna C. Thrombectomy for a Patient with Concomitant Acute Cervical Internal Carotid and Middle Cerebral Artery Occlusion: Video Case. Neurosurgery. 2019 Jul 1; 85 (suppl_1):S74-S75
    View PubMed
  28. Hu LS, Yoon H, Eschbacher JM, Baxter LC, Dueck AC, Nespodzany A, Smith KA, Nakaji P, Xu Y, Wang L, Karis JP, Hawkins-Daarud AJ, Singleton KW, Jackson PR, Anderies BJ, Bendok BR, Zimmerman RS, Quarles C, Porter-Umphrey AB, Mrugala MM, Sharma A, Hoxworth JM, Sattur MG, Sanai N, Koulemberis PE, Krishna C, Mitchell JR, Wu T, Tran NL, Swanson KR, Li J. Accurate Patient-Specific Machine Learning Models of Glioblastoma Invasion Using Transfer Learning. AJNR Am J Neuroradiol. 2019 Mar; 40 (3):418-425 Epub 2019 Feb 28
    View PubMed
  29. Bendok BR, Sattur MG, Welz ME, Abi-Aad KR, Krishna C, Urday LK. Patient Selection and Technical Nuances for Microsurgical Clipping of Carotid-Ophthalmic Aneurysms: 2-Dimensional Operative Video. Oper Neurosurg (Hagerstown). 2018 Aug 1; 15 (2):245
    View PubMed
  30. Tian F, Abi-Aad KR, Krishna C, Bendok BR. The DEFUSE Trial: An Even Brighter DAWN for Patients With Acute Stroke and An Invigorated Role for Neurosurgeons in Acute Stroke Care. Neurosurgery. 2018 Jul 1; 83 (1):E1-E2
    View PubMed
  31. Aoun RJN, Sattur MG, Krishna C, Bendok BR. Microsurgical Resection of a Type 1 Spinal Dural Arteriovenous Fistula: A 3-Dimensional Operative Video. Oper Neurosurg (Hagerstown). 2018 Mar 1; 14 (3):313
    View PubMed
  32. Aoun RJN, Sattur MG, Krishna C, Gupta A, Welz ME, Nanney AD 3rd, Koht AH, Tate MC, Noe KH, Sirven JI, Anderies BJ, Bolton PB, Trentman TL, Zimmerman RS, Swanson KR, Bendok BR. Awake Surgery for Brain Vascular Malformations and Moyamoya Disease. World Neurosurg. 2017 Sep; 105:659-671 Epub 2017 Apr 02
    View PubMed
  33. Gupta A, Sattur MG, Aoun RJN, Krishna C, Bolton PB, Chong BW, Demaerschalk BM, Lyons MK, McClendon J Jr, Patel N, Sen A, Swanson K, Zimmerman RS, Bendok BR. Hemicraniectomy for Ischemic and Hemorrhagic Stroke: Facts and Controversies. Neurosurg Clin N Am. 2017 Jul; 28 (3):349-360
    View PubMed
  34. Rangel-Castilla L, Munich SA, Jaleel N, Cress MC, Krishna C, Sonig A, Snyder KV, Siddiqui AH, Levy EI. Patency of anterior circulation branch vessels after Pipeline embolization: longer-term results from 82 aneurysm cases. J Neurosurg. 2017 Apr; 126: (4)1064-1069.
    View PubMed
  35. Lyons MK, Hoxworth JM, McClendon J, Krishna CX, Patel NP. Spontaneous resolution of ruptured intracranial pial arteriovenous fistula following spinal surgery. Neuroradiol J. 2017 Apr; 30 (2):175-179 Epub 2017 Feb 02
    View PubMed
  36. Pines AR, Alghoul MS, Hamade YJ, Sattur MG, Aoun RJN, Halasa TK, Krishna C, Zammar SG, El Tecle NE, El Ahmadieh TY, Aoun SG, Byrne RW, Harrop JS, Ragel BT, Resnick DK, Lonser RR, Selden NR, Bendok BR. Assessment of the Interrater Reliability of the Congress of Neurological Surgeons Microanastomosis Assessment Scale. Oper Neurosurg (Hagerstown). 2017 Feb 1; 13 (1):108-112
    View PubMed
  37. Birch BD, Aoun RJN, Elbert GA, Patel NP, Krishna C, Lyons MK. Minimally Invasive Tubular Resection of Lumbar Synovial Cysts: Report of 40 Consecutive Cases. World Neurosurg. 2016 Oct; 94:188-196 Epub 2016 July 09
    View PubMed
  38. Rahme RJ, Pines AR, Krishna C, Bendok BR. Understanding Rupture Risk Factors for Intracranial Aneurysms: Which Ticking Time Bomb Needs to be Defused? Neurosurgery 2016 Oct; 79 (4):N11-2
    View PubMed
  39. Liebelt BD, Haider AS, Steele WJ, Krishna C, Blacklock JB. Spinal Schwannoma and Meningioma Mimicking a Single Mass at the Craniocervical Junction Subsequent to Remote Radiation Therapy for Acne Vulgaris. World Neurosurg. 2016 Sep; 93:484.e13-6 Epub 2016 July 20
    View PubMed
  40. Rangel-Castilla L, Gandhi S, Munich SA, Cress MC, Sonig A, Krishna C, Hopkins LN, Snyder KV, Levy EI, Siddiqui AH. Experience with vertebral artery origin stenting and ostium dilatation: results of treatment and clinical outcomes. J Neurointerv Surg. 2016 May; 8: (5)476-80.
    View PubMed
  41. Munich SA, Cress MC, Rangel-Castilla L, Krishna C, Siddiqui AH, Snyder KV. Importance of repeat angiography in the diagnosis of iatrogenic anterior cerebral artery territory pseudoaneurysm following endoscopic sinus surgery. J Neurointerv Surg. 2016 May; 8: (5)e20.
    View PubMed
  42. Rangel-Castilla L, Cress MC, Munich SA, Sonig A, Krishna C, Gu EY, Snyder KV, Hopkins LN, Siddiqui AH, Levy EI. Feasibility, Safety, and Periprocedural Complications of Pipeline Embolization for Intracranial Aneurysm Treatment Under Conscious Sedation: University at Buffalo Neurosurgery Experience. Neurosurgery. 2015 Sep; 11 Suppl 3:426-30.
    View PubMed
  43. Krishna C, Sonig A, Natarajan SK, Siddiqui AH. The expanding realm of endovascular neurosurgery: flow diversion for cerebral aneurysm management. Methodist Debakey Cardiovasc J. 2014 Oct-Dec; 10(4):214-9.
    View PubMed
  44. Gist TL, Rangel-Castilla L, Krishna C, Roman GC, Cech DA, Diaz O. Endovascular management of six simultaneous intracranial dural arteriovenous fistulas in a single patient. J Neurointerv Surg. 2014 Mar; 6(2):e16. Epub 2013 Mar 14.
    View PubMed
  45. Gist TL, Rangel-Castilla L, Krishna C, Roman GC, Cech DA, Diaz O. Endovascular management of six simultaneous intracranial dural arteriovenous fistulas in a single patient. BMJ Case Rep. 2013; 2013. Epub 2013 Mar 07.
    View PubMed
  46. Rangel-Castilla L, Holman PJ, Krishna C, Trask TW, Klucznik RP, Diaz OM. Spinal extradural arteriovenous fistulas: a clinical and radiological description of different types and their novel treatment with Onyx. J Neurosurg Spine. 2011 Nov; 15(5):541-9. Epub 2011 Jul 29.
    View PubMed
  47. Rangel-Castilla L, Krishna C, Klucznik R, Diaz O. Endovascular embolization with Onyx in the management of sinus pericranii: a case report. Neurosurg Focus. 2009 Nov; 27(5):E13.
    View PubMed