Proper Use

Drug information provided by: IBM Micromedex

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

This medicine should come with a Medication Guide. It is very important that you read and understand this information. Be sure to ask your doctor about anything you do not understand.

Take this medicine without food, at least 2 hours after the evening meal.

Swallow the capsule whole with a glass of water. Do not break, crush, chew, dissolve, or open it. If you cannot swallow the capsules, tell your doctor right away.

Carefully follow your doctor's instructions about low-fat diet. This medicine is part of a complete plan for lowering bad cholesterol in your blood.

Your doctor may also want you to take supplements (eg, vitamin E, fatty acids) each day while you are using this medicine. This will help prevent stomach problems, such as trouble getting some nutrients into your body.

If you are also using cholestyramine (Questran®) or colesevelam (Welchol®), take it at least 4 hours before or after you take this medicine.

Do not drink more than 1 alcoholic drink per day with lomitapide. This could cause unwanted effects on the liver.

Grapefruit juice should be avoided while taking this medicine.


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (capsules):
    • For lowering bad cholesterol:
      • Adults—At first, 5 milligrams (mg) once a day. Your doctor may adjust your dose as needed and tolerated. However, the dose is usually not more than 60 mg per day.
      • Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

If you stop taking this medicine for more than a week, call your doctor right away before restarting treatment.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.