Side Effects

Drug information provided by: Micromedex

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

  1. Bone or joint pain
  2. burning, redness, itching, or other signs of eye inflammation
  3. difficulty with moving
  4. nosebleeds
  5. scaling, redness, burning, pain, or other signs of inflammation of the lips
  6. skin infection or rash


  1. Abdominal or stomach pain (severe)
  2. attempts at suicide or thoughts of suicide (usually stops after medicine is stopped)
  3. back pain
  4. bleeding or inflammation of the gums
  5. blurred vision or other changes in vision
  6. changes in behavior
  7. decreased vision after sunset or before sunrise (sudden or may continue after medicine is stopped)
  8. diarrhea (severe)
  9. headache (severe or continuing)
  10. mental depression
  11. nausea and vomiting
  12. pain or tenderness of the eyes
  13. pain, tenderness, or stiffness in the muscles (long-term treatment)
  14. rectal bleeding
  15. yellow eyes or skin

Incidence not known

  1. Black, tarry stools
  2. bloating
  3. bloody cough
  4. bloody or cloudy urine
  5. bone pain, tenderness, or aching
  6. burning or stinging of the skin
  7. chest pain
  8. confusion
  9. constipation
  10. convulsions
  11. cough or hoarseness
  12. dark-colored urine
  13. decrease in height
  14. difficulty breathing
  15. difficulty speaking
  16. difficulty swallowing
  17. discharge from the eyes
  18. dizziness
  19. double vision
  20. ear pain
  21. excessive tearing
  22. fainting
  23. fast, irregular, pounding, or racing heartbeat or pulse
  24. fever with or without chills
  25. fractures and/or delayed healing
  26. heartburn
  27. high blood pressure
  28. hives or skin rash
  29. inability to move the arms, legs, or facial muscles
  30. inability to speak
  31. indigestion
  32. inflamed tissue from infection
  33. irregular yellow patch or lump on the skin
  34. irritation
  35. joint pain, redness, stiffness, or swelling
  36. lack or slowing of normal growth in children
  37. loosening of the fingernails
  38. loss of appetite
  39. loss of bladder control
  40. loss or change in hearing
  41. muscle cramps, spasms, or weakness
  42. pain in the ribs, arms, or legs
  43. pain or burning in the throat
  44. pain or tenderness around the eyes and cheekbones
  45. painful cold sores or blisters on the lips, nose, eyes, or genitals
  46. painful or difficult urination
  47. pains in the chest, groin, or legs, especially calves of the legs
  48. pains in the stomach, side, or abdomen, possibly radiating to the back
  49. pale skin
  50. pinpoint red spots on the skin
  51. redness or soreness around the fingernails
  52. redness, soreness, or itching skin
  53. sensitivity of the eyes to sunlight
  54. sneezing
  55. sores, ulcers, or white spots on the lips or tongue or inside the mouth
  56. stuffy or runny nose
  57. sudden loss of consciousness
  58. sudden loss of coordination
  59. sudden onset of severe acne on the chest and trunk
  60. sudden onset of slurred speech
  61. swelling of the eyelids, face, lips, hands, lower legs, or feet
  62. swollen, painful or tender lymph glands in the neck, armpit, or groin
  63. tightness in the chest
  64. unusual bleeding or bruising
  65. unusual weight gain or loss
  66. use of extreme physical or emotional force
  67. watery or bloody diarrhea

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Crusting of the skin
  2. difficulty in wearing contact lenses (may continue after medicine is stopped)
  3. dryness of the eyes (may continue after treatment is stopped)
  4. dryness of the mouth or nose
  5. dryness or itching of the skin
  6. headache (mild)
  7. increased sensitivity of the skin to sunlight
  8. peeling of the skin on palms of the hands or soles of the feet
  9. stomach upset
  10. thinning of the hair (may continue after treatment is stopped)

Incidence not known

  1. Abnormal menstruation
  2. burning, crawling, itching, numbness, prickling, “pins and needles”, or tingling feeling
  3. changes in fingernails or toenails
  4. continuing ringing or buzzing, or other unexplained noise in the ears
  5. dandruff
  6. darkening of the skin
  7. flushing
  8. hair abnormalities
  9. hair loss
  10. increased hair growth, especially on the face
  11. lightening of normal skin color
  12. lightening of treated areas of dark skin
  13. nervousness
  14. oily skin
  15. redness of the face
  16. severe sunburn
  17. skin rash, encrusted, scaly and oozing
  18. stomach burning
  19. sweating
  20. trouble sleeping
  21. unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
  22. unusually warm skin of the face
  23. voice changes

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.