Description and Brand Names

Drug information provided by: IBM Micromedex

US Brand Name

  1. Ala-Hist AC
  2. Ala-Hist DHC
  3. Alavert-D 12-Hour
  4. Aldex D
  5. Alka-Seltzer Plus Cold and Sinus
  6. AllanVan-S
  7. Allegra-D
  8. Aller-Chlor
  9. Allerx-D
  10. Allfen CD
  11. Allres PD
  12. Amibid LA
  13. Benadryl
  14. BPM Pseudo
  15. Bromcomp HC
  16. Bromfed-PD
  17. BroveX CB
  18. By-Ache
  19. Canges-HC
  20. Ceron
  21. Ceron-DM
  22. Chlor-Trimeton Nasal Decongestant
  23. Clarinex-D
  24. Codimal DH
  25. Cotab A
  26. Cotabflu
  27. Cypex-LA
  28. Deconamine SR
  29. Delsym
  30. Dexphen wC
  31. Donatussin DC
  32. Donnatussin
  33. D-Tann HC
  34. EndaCof-DC
  35. FluTuss XP
  36. Genapap Sinus
  37. G Phen DM
  38. HC Tussive
  39. Histex PD
  40. Humibid DM
  41. Hycodan
  42. Hycofenix
  43. Hydone
  44. HyTan
  45. Kie
  46. Levall 12
  47. Lusonal
  48. Maxiflu CD
  49. Maxiphen CD
  50. M-End Max D
  51. Mucinex D
  52. Nasop
  53. Notuss-Forte
  54. Notuss-NX
  55. Notuss-NXD
  56. Novahistine DH
  57. Pancof HC
  58. Pediatex 12
  59. Pediatex 12D
  60. Pediatex 12DM
  61. Pediatex-D
  62. Phenergan wCodeine
  63. Phenflu CD
  64. Phenylephrine CM
  65. Phenylhistine
  66. Poly-Tussin AC
  67. Poly-Tussin DHC
  68. Pro-Clear AC
  69. Promethazine VC With Codeine
  70. Pro-Red AC
  71. RelaTuss HC
  72. Robitussin
  73. Robitussin DM
  74. Ryneze
  75. Semprex-D
  76. SSKI
  77. Stahist
  78. Sudafed
  79. SymTan
  80. SymTan A
  81. Tanafed DMX
  82. Tannate Pediatric
  83. Tessalon Perles
  84. Tricold Pediatric Drops
  85. Tripohist D
  86. Tussi-12 S
  87. TussiCaps
  88. Tuzistra XR
  89. Tylenol
  90. Uni-Tann D
  91. Vituz
  92. Xpect-PE
  93. Y-Cof DM
  94. Z-COF DM
  95. Zhist
  96. Zodryl DAC 25
  97. Zotex-D
  98. Zymine
  99. Zymine HC
  100. ZyrTEC-D

Canadian Brand Name

  1. Actifed Sinus Regular
  2. Adult Nighttime ColdFlu Relief - Cherry Flavor
  3. Adult Nighttime ColdFlu Relief - Original Flavor
  4. Allergy Sinus Medication Extra Strength
  5. Atoma Night Adult ColdFlu Relief
  6. Balminil
  7. Balminil Dm Children
  8. Balminil Dm Sugar-Free
  9. Balminil Expectorant
  10. Balminil Expectorant Sugar-Free
  11. Balminil With Sugar


Cough/cold combinations are used mainly to relieve the cough due to colds, influenza, or hay fever. They are not to be used for the chronic cough that occurs with smoking, asthma, or emphysema or when there is an unusually large amount of mucus or phlegm (pronounced flem) with the cough.

Cough/cold combination products contain more than one ingredient. For example, some products may contain an antihistamine, a decongestant, and an analgesic, in addition to a medicine for coughing. If you are treating yourself, it is important to select a product that is best for your symptoms. Also, in general, it is best to buy a product that includes only those medicines you really need. If you have questions about which product to buy, check with your pharmacist.

Since different products contain ingredients that will have different precautions and side effects, it is important that you know the ingredients of the medicine you are taking. The different kinds of ingredients that may be found in cough/cold combinations include:

Antihistamines—Antihistamines are used to relieve or prevent the symptoms of hay fever and other types of allergy. They also help relieve some symptoms of the common cold, such as sneezing and runny nose. They work by preventing the effects of a substance called histamine, which is produced by the body. Some examples of antihistamines contained in these combinations are:

  • Bromodiphenhydramine
  • Brompheniramine
  • Carbinoxamine
  • Chlorpheniramine
  • Dexchlorpheniramine
  • Diphenhydramine
  • Doxylamine
  • Phenindamine
  • Pheniramine
  • Phenyltoloxamine
  • Pyrilamine
  • Promethazine
  • Triprolidine

Decongestants—Decongestants produce a narrowing of blood vessels. This leads to clearing of nasal congestion. However, this effect may also increase blood pressure in patients who have high blood pressure. These include:

  • Ephedrine
  • Phenylephrine
  • Pseudoephedrine

Antitussives—Antitussives help relieve coughing and are some contain a narcotic. These antitussives act directly on the cough center in the brain. Narcotics may become habit-forming, causing mental or physical dependence, if used for a long time. Physical dependence may lead to withdrawal side effects when you stop taking the medicine.

Narcotic antitussives

  • Codeine
  • Dihydrocodeine
  • Hydrocodone
  • Hydromorphone

Non-narcotic antitussives

  • Carbetapentane
  • Caramiphen
  • Dextromethorphan

Expectorants—Expectorants work by loosening the mucus or phlegm in the lungs. The main expectorant used in cough and cold medicines is guaifenesin. Other ingredients added as expectorants (for example, ammonium chloride, calcium iodide, iodinated glycerol, ipecac, potassium guaiacolsulfonate, potassium iodide, and sodium citrate) have not been proven to be effective. In general, the best thing you can do to loosen mucus or phlegm is to drink plenty of water.

Analgesics—Analgesics are used in these combination medicines to help relieve the aches and pain that may occur with the common cold. These include:

  • Acetaminophen
  • Aspirin
  • Other salicylates such as salicylamide and sodium salicylate

The use of too much acetaminophen and salicylates at the same time may cause kidney damage or cancer of the kidney or urinary bladder. This may occur if large amounts of both medicines are taken together for a long time. However, taking the recommended amounts of combination medicines that contain both acetaminophen and a salicylate for short periods of time has not been shown to cause these unwanted effects.

Anticholinergics—Anticholinergics, such as homatropine may help produce a drying effect in the nose and chest.

These cough and cold combinations are available both over-the-counter (OTC) and with your doctor's prescription.

Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .

This product is available in the following dosage forms:

  • Solution
  • Tablet, Chewable
  • Tablet, Extended Release, 24 HR
  • Tablet, Extended Release
  • Tablet, Extended Release, 12 HR
  • Tablet
  • Syrup
  • Liquid
  • Capsule, Liquid Filled
  • Capsule
  • Elixir
  • Suspension, Extended Release
  • Lozenge/Troche
  • Suspension
  • Tablet, Effervescent
  • Packet
  • Powder for Solution
  • Powder for Suspension
  • Film