Interactions

Mixing aloe with the following medicines may cause harm:

• Anticoagulants and antiplatelet medicines, herbs and supplements. These types of medicines, herbs and supplements slow blood clotting. Taking aloe by mouth also might slow blood clotting. Taking aloe by mouth with these types of medicines might lead to more bleeding.
• Digoxin (Lanoxin). Taking aloe latex by mouth can lower potassium levels. Low potassium might raise the side effects of digoxin. Don't take aloe latex and digoxin together.
• Diabetes medicines. Taking aloe gel by mouth while taking diabetes medicines might raise the risk of low blood sugar, called hypoglycemia.
• Other medicines taken by mouth. Taking aloe latex by mouth can keep the body from taking in other medicines. This might lower how well those medicines work.
• Sevoflurane (Sojourn, Ultane). This medicine used to cause a sleeplike state during surgery, called anesthesia, may slow blood clotting. Taking aloe by mouth also may slow blood clotting. Taken together, they might cause too much bleeding during surgery.
• Stimulant laxatives. Taking aloe latex with medicines that help move stool through the body might make the bowels work too hard. This can lead to loss of fluids, called dehydration.
• Warfarin (Jantoven). Taking aloe latex by mouth can cause loose stools. This can add to the effects of warfarin, a blood-thinning medicine. This can raise the risk of bleeding.
• Water pills, also called diuretics. Taking aloe latex by mouth with diuretics might lower the body's potassium levels too much, leading to a condition called hypokalemia.