Before Using

Drug information provided by: Merative, Micromedex®

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to medicines in this group or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Although there is no specific information comparing use of antimyasthenics in children with use in other age groups, these medicines are not expected to cause different side effects or problems in children than they do in adults.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is not much information comparing use of antimyasthenics in the elderly with use in other age groups, these medicines are not expected to cause different side effects or problems in older people than they do in younger adults.

Pregnancy

Antimyasthenics have not been reported to cause birth defects; however, muscle weakness has occurred temporarily in some newborn babies whose mothers took antimyasthenics during pregnancy.

Breastfeeding

Antimyasthenics have not been reported to cause problems in nursing babies.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking any of these medicines, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using medicines in this class with any of the following medicines is not recommended. Your doctor may decide not to treat you with a medication in this class or change some of the other medicines you take.

  • Atropine
  • Bepridil
  • Bromopride
  • Cisapride
  • Dronedarone
  • Fluconazole
  • Ketoconazole
  • Levoketoconazole
  • Mesoridazine
  • Pimozide
  • Piperaquine
  • Posaconazole
  • Saquinavir
  • Sparfloxacin
  • Terfenadine
  • Thioridazine
  • Viloxazine
  • Ziprasidone

Using medicines in this class with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Abiraterone Acetate
  • Acebutolol
  • Acetophenazine
  • Aclidinium
  • Acrivastine
  • Adagrasib
  • Alcaftadine
  • Alfentanil
  • Alfuzosin
  • Amantadine
  • Ambenonium
  • Amdinocillin
  • Amdinocillin Pivoxil
  • Amifampridine
  • Amineptine
  • Aminophylline
  • Amiodarone
  • Amisulpride
  • Amitriptyline
  • Amitriptylinoxide
  • Amoxapine
  • Amphetamine
  • Ampicillin
  • Anagrelide
  • Anisotropine
  • Antazoline
  • Apomorphine
  • Aripiprazole
  • Aripiprazole Lauroxil
  • Arsenic Trioxide
  • Asenapine
  • Astemizole
  • Atazanavir
  • Atenolol
  • Atomoxetine
  • Atropine
  • Azatadine
  • Azelastine
  • Azithromycin
  • Azlocillin
  • Bacampicillin
  • Baclofen
  • Bedaquiline
  • Belladonna Alkaloids
  • Benperidol
  • Benzhydrocodone
  • Benzphetamine
  • Bepotastine
  • Betaxolol
  • Bisoprolol
  • Bornaprine
  • Bromodiphenhydramine
  • Bromperidol
  • Brompheniramine
  • Buclizine
  • Bupivacaine
  • Buprenorphine
  • Bupropion
  • Buserelin
  • Butorphanol
  • Butriptyline
  • Butylscopolamine
  • Capmatinib
  • Carbamazepine
  • Carbenicillin
  • Carbinoxamine
  • Carteolol
  • Carvedilol
  • Celiprolol
  • Ceritinib
  • Chlorambucil
  • Chloroquine
  • Chlorotrianisene
  • Chlorpheniramine
  • Chlorphenoxamine
  • Chlorpromazine
  • Cimetropium
  • Cinacalcet
  • Cinnarizine
  • Ciprofloxacin
  • Citalopram
  • Clarithromycin
  • Clemastine
  • Clemizole
  • Clidinium
  • Clofazimine
  • Clomipramine
  • Clothiapine
  • Cloxacillin
  • Clozapine
  • Cobicistat
  • Cocaine
  • Codeine
  • Conjugated Estrogens
  • Crizotinib
  • Cyclacillin
  • Cyclizine
  • Cyclobenzaprine
  • Cyclopentolate
  • Cyclosporine
  • Cyproheptadine
  • Dabrafenib
  • Darifenacin
  • Dasatinib
  • Degarelix
  • Delamanid
  • Demecarium
  • Desipramine
  • Deslorelin
  • Desvenlafaxine
  • Deutetrabenazine
  • Dexbrompheniramine
  • Dexchlorpheniramine
  • Dexmedetomidine
  • Dextroamphetamine
  • Dibenzepin
  • Dicloxacillin
  • Dicyclomine
  • Dienestrol
  • Diethylstilbestrol
  • Difenoxin
  • Dihydrocodeine
  • Dimenhydrinate
  • Dimethindene
  • Diphenhydramine
  • Diphenylpyraline
  • Disopyramide
  • Distigmine
  • Dixyrazine
  • Dofetilide
  • Dolasetron
  • Domperidone
  • Donepezil
  • Dothiepin
  • Doxepin
  • Doxylamine
  • Droperidol
  • Duloxetine
  • Ebastine
  • Echothiophate
  • Edrophonium
  • Efavirenz
  • Eliglustat
  • Emedastine
  • Encorafenib
  • Enflurane
  • Entrectinib
  • Epinastine
  • Eribulin
  • Erythromycin
  • Escitalopram
  • Esmolol
  • Esterified Estrogens
  • Estradiol
  • Estramustine
  • Estriol
  • Estrone
  • Estropipate
  • Ethinyl Estradiol
  • Ethopropazine
  • Etrasimod
  • Etravirine
  • Famotidine
  • Felbamate
  • Fentanyl
  • Fesoterodine
  • Fexinidazole
  • Fingolimod
  • Flavoxate
  • Flecainide
  • Floxacillin
  • Fluconazole
  • Flunarizine
  • Fluoxetine
  • Fluphenazine
  • Fluvoxamine
  • Formoterol
  • Foscarnet
  • Fosphenytoin
  • Fostemsavir
  • Galantamine
  • Gatifloxacin
  • Gemifloxacin
  • Gepirone
  • Givosiran
  • Glasdegib
  • Glycopyrrolate
  • Gonadorelin
  • Goserelin
  • Granisetron
  • Guanidine
  • Halofantrine
  • Haloperidol
  • Hetacillin
  • Histrelin
  • Homatropine
  • Hydrocodone
  • Hydromorphone
  • Hydroquinidine
  • Hydroxyamphetamine
  • Hydroxychloroquine
  • Hydroxyzine
  • Hyoscyamine
  • Ibutilide
  • Iloperidone
  • Imipramine
  • Indalpine
  • Inotuzumab Ozogamicin
  • Iprindole
  • Isoflurophate
  • Isoniazid
  • Isopropamide
  • Itraconazole
  • Ivabradine
  • Ivosidenib
  • Ketamine
  • Ketotifen
  • Labetalol
  • Lapatinib
  • Lefamulin
  • Lenvatinib
  • Leuprolide
  • Levobunolol
  • Levocabastine
  • Levofloxacin
  • Levomilnacipran
  • Levorphanol
  • Lidocaine
  • Lindane
  • Lisdexamfetamine
  • Lithium
  • Lofepramine
  • Lofexidine
  • Loxapine
  • Lumefantrine
  • Macimorelin
  • Mebeverine
  • Mebhydrolin
  • Meclizine
  • Mefenamic Acid
  • Mefloquine
  • Melitracen
  • Melperone
  • Mepenzolate
  • Meperidine
  • Mestranol
  • Methadone
  • Methamphetamine
  • Methantheline
  • Methdilazine
  • Methicillin
  • Methixene
  • Methotrimeprazine
  • Methylphenidate
  • Metipranolol
  • Metoclopramide
  • Metopimazine
  • Metoprolol
  • Metronidazole
  • Mezlocillin
  • Mifepristone
  • Milnacipran
  • Mirtazapine
  • Mizolastine
  • Mobocertinib
  • Moricizine
  • Morphine
  • Moxifloxacin
  • Nadolol
  • Nafarelin
  • Nafcillin
  • Nalbuphine
  • Nalidixic Acid
  • Nebivolol
  • Nefazodone
  • Nelfinavir
  • Neostigmine
  • Niaprazine
  • Nilotinib
  • Norfloxacin
  • Nortriptyline
  • Octreotide
  • Ofloxacin
  • Olanzapine
  • Olopatadine
  • Ondansetron
  • Opipramol
  • Orphenadrine
  • Osilodrostat
  • Osimertinib
  • Oxacillin
  • Oxaliplatin
  • Oxatomide
  • Oxprenolol
  • Oxybutynin
  • Oxycodone
  • Oxymorphone
  • Ozanimod
  • Pacritinib
  • Paliperidone
  • Panobinostat
  • Paroxetine
  • Pasireotide
  • Pazopanib
  • Peginterferon Alfa-2b
  • Penbutolol
  • Penicillin G
  • Penicillin V
  • Pentamidine
  • Pentazocine
  • Perazine
  • Periciazine
  • Perphenazine
  • Phenindamine
  • Pheniramine
  • Phenobarbital
  • Phenylpropanolamine
  • Phenyltoloxamine
  • Physostigmine
  • Pimavanserin
  • Pinaverium
  • Pindolol
  • Pipamperone
  • Piperacillin
  • Pipotiazine
  • Pirenzepine
  • Pitolisant
  • Pivampicillin
  • Pixantrone
  • Pizotyline
  • Polyestradiol Phosphate
  • Ponesimod
  • Posaconazole
  • Practolol
  • Primidone
  • Probucol
  • Procainamide
  • Procaine
  • Prochlorperazine
  • Promazine
  • Promestriene
  • Promethazine
  • Propafenone
  • Propantheline
  • Propicillin
  • Propiverine
  • Propizepine
  • Propoxyphene
  • Propranolol
  • Protriptyline
  • Pyrilamine
  • Quetiapine
  • Quinestrol
  • Quinidine
  • Quinine
  • Quizartinib
  • Ranolazine
  • Relugolix
  • Remifentanil
  • Ribociclib
  • Rilpivirine
  • Risperidone
  • Ritlecitinib
  • Ritonavir
  • Rivastigmine
  • Scopolamine
  • Selpercatinib
  • Sertindole
  • Sertraline
  • Sevoflurane
  • Sibutramine
  • Siponimod
  • Sodium Phosphate
  • Sodium Phosphate, Dibasic
  • Sodium Phosphate, Monobasic
  • Solifenacin
  • Sorafenib
  • Sotalol
  • Succinylcholine
  • Sufentanil
  • Sulbenicillin
  • Sulpiride
  • Sultamicillin
  • Sunitinib
  • Tacrine
  • Tacrolimus
  • Tamoxifen
  • Tapentadol
  • Telaprevir
  • Telavancin
  • Telithromycin
  • Temocillin
  • Terbinafine
  • Tetrabenazine
  • Theophylline
  • Thiethylperazine
  • Thiopropazate
  • Thioproperazine
  • Thonzylamine
  • Tianeptine
  • Tibolone
  • Ticarcillin
  • Timiperone
  • Timolol
  • Tiotropium
  • Tolterodine
  • Toremifene
  • Tramadol
  • Trazodone
  • Triclabendazole
  • Trifluoperazine
  • Triflupromazine
  • Trimeprazine
  • Trimipramine
  • Tripelennamine
  • Triprolidine
  • Triptorelin
  • Tropicamide
  • Trospium
  • Umeclidinium
  • Valethamate
  • Vandetanib
  • Vardenafil
  • Vemurafenib
  • Venlafaxine
  • Vilanterol
  • Vinflunine
  • Voclosporin
  • Voriconazole
  • Vorinostat
  • Zuclopenthixol

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using medicines in this class with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use your medicine, or give you special instructions about the use of food, alcohol, or tobacco.

  • Bitter Orange
  • Grapefruit Juice
  • Tobacco

Other Medical Problems

The presence of other medical problems may affect the use of medicines in this class. Make sure you tell your doctor if you have any other medical problems, especially:

  • Intestinal blockage or
  • Urinary tract blockage or
  • Urinary tract infection—These medicines may make the condition worse.