Testing for specific STIs

These guidelines for specific STIs can help you decide if STI testing is right for you.

Chlamydia and gonorrhea

National guidelines recommend yearly screening for:

• Sexually active women under age 25
• Women older than 25 and at increased risk of STIs — such as having sex with a new partner or multiple partners
• Men who have sex with men
• People with HIV
• Transgender women who have sex with men
• People who have been forced to have intercourse or engage in sexual activity against their will

Health care providers screen people for chlamydia and gonorrhea using a swab test or urine test. The sample is then studied in a lab. Screening is important, because if you don't have symptoms, you may not know that you're infected.

HIV, syphilis and hepatitis

The U.S. Preventive Services Taskforce encourages HIV testing, at least once, as a routine part of health care if you're between the ages of 15 and 65. Younger teens or older adults should be tested if they have a high risk of an STI. The Centers for Disease Control and Prevention (CDC) advises at least yearly HIV testing if you're at high risk of infection.

National guidelines recommend hepatitis B screening for people age 18 and older at least once, and with a test that includes a few different markers of the virus. Guidelines also recommend hepatitis C screening for all adults. Vaccines are available for hepatitis A and B and are usually given at birth. Unvaccinated adults can be vaccinated if they are at high risk of getting hepatitis A or B.

If you have any of the following risk factors, talk to your health care provider about testing for HIV, syphilis or hepatitis:

• Symptoms of infection
• Positive test for another STI, which puts you at greater risk of other STIs
• Having more than one sexual partner, or if your partner has had multiple partners, since your last test
• Intravenous (IV) drug use
• Newly diagnosed hepatitis C infection
• Having been in jail or prison
• Men who have sex with men
• Being pregnant or planning to become pregnant
• Being forced to have intercourse or engage in sexual activity against your will

Your health care provider tests you for syphilis by taking either a blood sample or a swab from any genital sores you might have. A lab specialist studies the sample in a lab. Your provider also takes a blood sample to test for HIV and hepatitis.

Genital herpes

Providers generally only recommend testing for genital herpes for people who have symptoms or other risk factors. But most people with herpes never have any symptoms but can still spread the herpes virus to others. Your health care provider may take a tissue sample or culture of blisters or early ulcers, if you have them, and send them to a lab. But a negative test doesn't always mean you don't have herpes, especially if you have symptoms.

A blood test also may tell if you had a past herpes virus infection, but results aren't always reliable. Some blood tests can help providers see which of the two main types of the herpes virus you have. Type 1 is the virus that usually causes cold sores, although it can also cause genital sores.

Type 2 is the virus that causes genital sores more often. Still, the results may not be clear, depending on how sensitive the test is and the stage of the infection. False-positive and false-negative results are possible.

HPV

Certain types of human papillomavirus (HPV) can cause cervical cancer. Other types of HPV can cause genital warts. Many sexually active people get HPV at some point in their lives but never have symptoms. Most of the time, the virus goes away on its own within two years.

Regular HPV testing isn't recommended for men. Instead, health care providers may choose to test men who have symptoms, such as genital warts. A sample of the wart is removed and sent to a lab. In women, HPV testing involves:

• Pap test. Pap tests, which check the cervix for irregular cells, are recommended every three years for women between ages 25 and 65.
• HPV test. Women between ages 25 and 65 should have an HPV test alone or an HPV test along with a Pap test every five years if previous test results were within the standard range. Testing may take place more often for those who are at high risk of cervical cancer or those who have irregular results on their Pap or HPV tests.

HPV is also linked to cancer of the vulva, vagina, penis, anus, and mouth and throat. Vaccines can protect both men and women from some types of HPV. But they're most effective when given between ages 9 and 26.