Diagnosis at Mayo Clinic

By Mayo Clinic Staff


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Systemic capillary leak syndrome is difficult to diagnose. You may undergo blood and urine tests and imaging studies. Your doctors may diagnose sudden, periodic "attacks" of this condition by seeing the following signs, symptoms and laboratory abnormalities and excluding other conditions that could cause them:

  • Concentrated blood
  • Low serum albumin in the blood
  • Presence of a distinct monoclonal protein in the blood or urine
  • Generalized body swelling
  • Muscle aches
  • Lightheadedness
  • Fatigue
  • Decreased or dark urine
Nov. 26, 2014