Research on coenzyme Q10, also called CoQ10, use for specific conditions and activities shows:

Heart conditions. CoQ10 may improve congestive heart failure symptoms. Although findings are mixed, CoQ10 might help lower blood pressure. Some research also suggests that when taken with other nutrients, CoQ10 might help people recover from bypass and heart valve surgeries.
Diabetes. Some research suggests that CoQ10 may help lower cholesterol in people with diabetes. The effect could lower their heart disease risk.
Parkinson's disease. Taking even high doses of CoQ10 doesn't seem to help with Parkinson's disease symptoms.
Statin-induced myopathy. Some research suggests that CoQ10 might help ease the muscle weakness and pain that can happen when taking statins. There isn't enough evidence to know for sure.
Migraines. Some research suggests CoQ10 might lower how often migraines happen or how long they last. People who get migraines usually have to take the supplement for three months before they may see a benefit.
Physical performance. Because CoQ10 helps the body make energy, it's thought this supplement might improve how well the body performs during exercise. But research in this area has not been conclusive.
Metabolic dysfunction-associated steatotic liver disease, also called MASLD. A small research study found that people taking CoQ10 had reduced amounts of fat in their livers compared with people who didn't take CoQ10. More studies are needed.