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Your biological siblings may also have one or two BCHE variants. Your full siblings have a 25 percent chance of having two BCHE variants, a 50 percent chance of having one BCHE variant, and a 25 percent chance of having no BCHE variants. Although the genetic risk of side effects with these medications is lower for someone with one variant than with two, if the anesthesiologist has this information, he or she may choose to use other anesthesia medications that would be safer.
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