Membranous nephropathy care at Mayo Clinic

Your Mayo Clinic care team

Kidney specialists (nephrologists) work with hypertension, transplant and tissue analysis specialists to accurately diagnose your disease and develop the best treatment plan. Mayo Clinic doctors will work closely with your local doctor to coordinate treatment and follow-up care.

Advanced diagnosis and treatment

Mayo Clinic is at the forefront of diagnosing membranous nephropathy. Specialists at Mayo Clinic are testing for certain immune system substances known as anti-PLA2R antibodies. High levels of anti-PLA2R antibodies are a sign of active disease. They've been linked to an increased risk of worsening kidney function. Anti-PLA2R antibodies are found in the blood of about 70 percent of people with membranous nephropathy.

Monitoring anti-PLA2R antibodies can also help guide treatment decisions and check response to therapy in people with membranous nephropathy.

Mayo Clinic doctors continually investigate possible new approaches in the treatment of membranous nephropathy. Your treatment of membranous nephropathy could include participation in a clinical trial, if you qualify. For example, Mayo Clinic researchers are currently studying the effectiveness of rituximab (Rituxan) versus cyclosporine in treating membranous nephropathy in a randomized, controlled clinical trial.

Nationally recognized expertise

Mayo Clinic in Rochester, Minn., ranks No. 1 for kidney disorders in the U.S. News & World Report Best Hospitals rankings. Mayo Clinic in Scottsdale, Ariz., ranks among the Best Hospitals for kidney disorders by U.S. News & World Report. Mayo Clinic in Jacksonville, Fla., is ranked high performing for kidney disorders by U.S. News & World Report.

Expertise and rankings

  • Experience. Doctors at Mayo Clinic treat about 250 people each year who have membranous nephropathy.
  • Expertise. The large number of kidney specialists (nephrologists) at Mayo Clinic allows some doctors to specialize and become skilled at specific aspects of kidney medicine, including glomerular diseases such as membranous nephropathy. Kidney specialists are experts at kidney biopsies and have an outstanding track record for safety. Mayo pathologists are world-renowned experts in interpreting biopsies.
  • Access to the latest knowledge. Mayo Clinic is on the forefront of testing antibodies that may be causing membranous nephropathy and new therapies to counteract these antibodies. By participating in clinical trials, you can get access to experimental treatments and help shape the course of future therapy for others.

Mayo Clinic in Rochester, Minn., ranks No. 1 for kidney disorders in the U.S. News & World Report Best Hospitals rankings. Mayo Clinic in Scottsdale, Ariz., ranks among the Best Hospitals for kidney disorders by U.S. News & World Report. Mayo Clinic in Jacksonville, Fla., is ranked high performing for kidney disorders by U.S. News & World Report.

Locations, travel and lodging

Mayo Clinic has major campuses in Phoenix and Scottsdale, Arizona; Jacksonville, Florida; and Rochester, Minnesota. The Mayo Clinic Health System has dozens of locations in several states.

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Costs and insurance

Mayo Clinic works with hundreds of insurance companies and is an in-network provider for millions of people.

In most cases, Mayo Clinic doesn't require a physician referral. Some insurers require referrals, or may have additional requirements for certain medical care. All appointments are prioritized on the basis of medical need.

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Please contact your insurance company to verify medical coverage and to obtain any needed authorization prior to your visit. Often, your insurer's customer service number is printed on the back of your insurance card.

Oct. 26, 2017