Hyperoxaluria occurs when you have too much oxalate in your urine. Oxalate is a natural chemical in your body, and it's also found in certain types of food. But too much oxalate in your urine can cause serious problems.
Hyperoxaluria can be caused by inherited (genetic) disorders, an intestinal disease or eating too many oxalate-rich foods. The long-term health of your kidneys depends on early diagnosis and prompt treatment of hyperoxaluria.
Oxalosis happens after the kidneys fail in people who have primary and intestinal causes of hyperoxaluria, and excess oxalate builds up in the blood. This can lead to oxalate deposits in blood vessels, bones and body organs.
Hyperoxaluria and oxalosis care at Mayo Clinic
Aug. 23, 2017
- Primary hyperoxaluria. Genetics Home Reference — National Institutes of Health. http://ghr.nlm.nih.gov/condition/primary-hyperoxaluria. Accessed Feb. 11, 2016.
- Learn more — Primary hyperoxaluria (PH). Rare Kidney Stone Consortium. http://www.rarediseasesnetwork.org/RKSC/PH/. Accessed Feb. 11, 2016.
- Niaudet P. Primary hyperoxaluria. http://www.uptodate.com/home. Accessed Feb. 11, 2016.
- Bope ET, et al. Renal calculus. In: Conn's Current Therapy 2016. Philadelphia, Pa.: Elsevier; 2016. http://www.clinicalkey.com. Accessed Feb. 24, 2016.
- What I need to know about kidney stones. National Kidney and Urologic Diseases Information Clearinghouse. http://www.niddk.nih.gov/health-information/health-topics/urologic-disease/kidney-stones-in-adults/Pages/ez.aspx. Accessed Feb. 11, 2016.
- Hoppe B. An update on primary hyperoxaluria. Nature Reviews Nephrology. 2012;8:467.
- Carrasco A, et al. Surgical management of stone disease in patients with primary hyperoxaluria. Urology. 2015;85:522.
- What are the signs of kidney failure? Urology Care Foundation. http://www.urologyhealth.org/urologic-conditions/kidney-(renal)-failure/symptoms. Accessed Feb. 22, 2016.
- Pearle MS, et al. Medical management of kidney stones: AUA guideline. The Journal of Urology. 2014;192:316.
- Lieske JC (expert opinion). Mayo Clinic, Rochester, Minn. April 21, 2016.
Hyperoxaluria and oxalosis