Departments and specialties
Mayo Clinic has one of the largest and most experienced practices in the United States,
with campuses in Arizona, Florida and Minnesota. Staff skilled in dozens of specialties work
together to ensure quality care and successful recovery.
Departments that treat this condition
Research
Mayo Clinic doctors and scientists are involved in research to improve understanding, screening and care for people with familial adenomatous polyposis (FAP). Mayo Clinic maintains a Colon Cancer Family Registry that collects data and biospecimens from thousands of families to help identify genes linked to colorectal cancer risk and to understand how genetic changes lead to disease. Researchers examine genetic interactions, biomarkers and other factors that may influence cancer development and prevention.
Mayo Clinic researchers also have studied the incidence and risk factors for gastric cancer in people with FAP, aiming to refine surveillance strategies and guide early intervention in rare but serious outcomes. These findings may help shape future recommendations for screening beyond the colon in high-risk patients.
Clinical trials at Mayo Clinic have explored potential therapies for FAP, such as study of erlotinib to reduce polyp burden in the upper gastrointestinal tract and investigations into novel agents such as guselkumab to evaluate effects on polyp number and growth. Participation in these trials offers access to emerging approaches under scientific study.
Publications
See a list of publications about familial adenomatous polyposis (FAP) by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.