In corticobasal degeneration, areas of your brain (including the cerebral cortex and basal ganglia) shrink and your nerve cells degenerate and die over time. This degeneration results in growing difficulty in movement on one or both sides of your body.
The condition may cause you to have poor coordination, stiffness, thinking (cognitive) difficulties, speech or language difficulty, or other problems.
Corticobasal degeneration care at Mayo Clinic
Dec. 01, 2016
- Factor SA, et al. Corticobasal degeneration. http://www.uptodate.com/home. Accessed Oct. 13, 2016.
- Riggin EA. Decision Support System. Mayo Clinic, Rochester, Minn. July 1, 2016.
- NINDS corticobasal degeneration information page. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/corticobasal_degeneration/corticobasal_degeneration.htm. Accessed Oct. 13, 2016.
- Daroff RB, et al. Neurodegenerative disease processes. In: Bradley's Neurology in Clinical Practice. 7th ed. Philadelphia, Pa.: Saunders Elsevier; 2016. https://www.clinicalkey.com. Accessed Oct. 13, 2016.
- Budson AE, et al. Corticobasal degeneration. In: Memory Loss, Alzheimer's Disease, and Dementia. 2nd ed. Philadelphia, Pa.: Elsevier; 2016. http://www.clinicalkey.com. Accessed Oct. 13, 2016.
- Graff-Radford N (expert opinion). Mayo Clinic, Rochester, Minn. Oct. 25, 2016.